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FGF2

  • Official Full Name

    Fibroblast Growth Factor 2 (basic)

  • Overview

    roblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.

  • Synonyms

    FGF2;fibroblast growth factor 2 (basic);BFGF;FGFB;HBGF-2;heparin-binding growth factor 2;prostatropin;OTTHUMP00000037513;basic fibroblast growth factor bFGF;Fgf-2

Recombinant Proteins

  • Human
  • Bovine
  • Rabbit
  • Mouse
  • Porcine
  • Zebrafish
  • Rat
  • Chicken
  • Bovine/Porcine
  • Cattle
  • Pig
  • E.coli
  • Yeast
  • Insect Cell
  • Barley Grain
  • Sf21 Insect Cell
  • Hordeum Vulgare
  • CHO-K1
  • E. coli
  • N/A
  • HEK293
  • Bovine Pituitary
  • Bovine brain
  • Oryza Sativa
  • Mammalian Cell
  • Wheat Germ
  • Human Cell
  • yeast
  • Bovine
  • Mouse
  • Human cells
  • HEK293T
  • CHO
  • Non
  • His
  • His&ERHV
  • C-His&Flag
  • His&S
  • GST
  • StrepII
  • Myc&DDK
  • HIS
  • His&MBP&Avi
  • His&Fc&Avi
  • His&Avi
  • His&SUMO
  • SUMO
  • HA
  • N-His-SUMO
  • N-His&C-Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
FGF2-13H Active Recombinant Human FGF2 Protein, Biotinylated E.coli Human Non Pro143-Ser288
FGF2-11H Recombinant Human Fibroblast Growth Factor-basic E.coli Human Non
FGF2-482H Recombinant Human FGF2 protein E.coli Human Non Pro143-Ser288
FGF2-001H Recombinant Human FGF2 Protein, His-tagged E.coli Human His 134-288
FGF2-18H Active Recombinant Human FGF2 Protein (143-288aa), Non-tagged E.coli Human Non 143-288 aa
FGF2-4381B Recombinant Bovine FGF2 Protein Yeast Bovine Non 145aa
FGF2-4387R Recombinant Rabbit FGF2 Protein Yeast Rabbit Non 145aa
FGF2-022E Active Recombinant Human FGF2 (143-288aa), Ala tagged E.coli Human Non
FGF2-12H Active Recombinant Human FGF2 E.coli Human Non 132-288 a.a.
FGF2-169H Active Recombinant Human FGF2 Insect Cell Human Non
FGF2-19H Active Recombinant Human FGF2 protein, ERHV-His-tagged Barley Grain Human His&ERHV
FGF2-1H Active Recombinant Human FGF basic protein E.coli Human Non
FGF2-730H Active Recombinant Human FGF2, Ala-tagged E.coli Human 143-288 a.a.
Fgf2-829M Active Recombinant Mouse Fgf2 protein(Ala11-Ser154), His-tagged E.coli Mouse His Ala11-Ser154
FGF2-8499H Active Recombinant Human FGF2, His-tagged Sf21 Insect Cell Human His
FGF2-8856H Active Recombinant Human Fibroblast Growth Factor 2 (basic) Hordeum Vulgare Human Non
FGF2-019B Active Recombinant Bovine FGF2 protein, His-tagged E.coli Bovine His Pro10~Ser155
FGF2-01HG Active GMP Recombinant Human bFGF Protein CHO-K1 Human
Fgf2-01M Active GMP Recombinant Mouse Fgf2 Protein, His-Tagged E.coli Mouse His
FGF2-01P Active GMP Recombinant Porcine FGF2 Protein, His-Tagged E.coli Porcine His
FGF2-049H Active Recombinant Human fibroblast growth factor 2 Protein, His&Flag tagged E. coli Human C-His&Flag 143-288aa
FGF2-1429H Recombinant Human FGF2 protein N/A Human Ala135-Ser288
FGF2-179HG Active GMP Recombinant Human FGF2 protein HEK293 Human Non
FGF2-34B Active Native Bovine bFGF Bovine Pituitary Bovine Non
FGF2-40B Active Native Bovine FGF2 Protein Bovine brain Bovine Non
FGF2-4766H Recombinant Human FGF2 protein, For Organoid Culture E. coli Human Non Gly132-Ser288
FGF2-754H Active Recombinant Human FGF2 protein Yeast Human Non
FGF2-014O Recombinant Human FGF2 Oryza Sativa Human Non
FGF2-018E Recombinant Bovine FGF2 protein E.coli Bovine Non 147
FGF2-1182B Recombinant Bovine Fibroblast Growth Factor 2 (basic) E.coli Bovine Non
FGF2-12089Z Recombinant Zebrafish FGF2 Mammalian Cell Zebrafish His
Fgf2-12M Recombinant Mouse Fgf2 protein E.coli Mouse Non 146
FGF2-198H Recombinant Human FGF2 protein, His/S-tagged E.coli Human His&S
Fgf2-199M Recombinant Mouse Fgf2 protein, His/S-tagged E.coli Mouse His&S
Fgf2-200R Recombinant Rat Fgf2 protein, His/S-tagged E.coli Rat His&S
FGF2-22H Recombinant Human FGF2 protein, GST-tagged Wheat Germ Human GST 189-288 a.a.
FGF2-2331R Recombinant Rat FGF2 Protein Mammalian Cell Rat His
FGF2-27258TH Recombinant Human FGF2, His-tagged Human His Full L. 134-288 a.a.
FGF2-27596TH Recombinant Human FGF2 Human Non Full L. 134-288 a.a.
FGF2-2784H Recombinant Human FGF2 protein, His-tagged E.coli Human His Phe159~Ser288
FGF2-2785R Recombinant Rabbit FGF2 protein, His-tagged E.coli Rabbit His Phe26~Ala153
FGF2-293H Recombinant Human FGF2, StrepII-tagged Human Cell Human StrepII 2-288, 287 a.a.
Fgf2-40R Recombinant Rat Fgf2 protein E.coli Rat Non 146
FGF2-41H Recombinant Human FGF2 protein, MYC/DDK-tagged HEK293 Human Myc&DDK
FGF2-567H Recombinant Human FGF2 protein E.coli Human Non 147
FGF2-5847M Recombinant Mouse FGF2 Protein Mammalian Cell Mouse His
FGF2-590H Recombinant Human FGF2 protein E.coli Human 146
FGF2-5H Active Recombinant Human Basic Fibroblast Growth Factor yeast Human Non
FGF2-650B Recombinant Bovine Fibroblast Growth Factor 2 Bovine Bovine Non
Fgf2-664M Recombinant Mouse Fibroblast Growth Factor 2 Mouse Mouse Non
FGF2-678H Recombinant Human Fibroblast Growth Factor 2 (basic) (aa 146) E.coli Human Non
Fgf2-680M Recombinant Mouse Fibroblast Growth Factor 2 E.coli Mouse Non
FGF2-6983C Recombinant Chicken FGF2 Mammalian Cell Chicken His
FGF2-91H Recombinant Human FGF2,His-tagged Insect Cell Human HIS
FGF2-638HCL Recombinant Human FGF2 cell lysate Insect Cell Human Non
bFGF-10A Recombinant bFGF agarose fast flow Non
DMABT-H18565 Mouse Anti-FGF2 Monoclonal Antibody Mouse Human Non
DMABT-H18566 Mouse Anti-FGF2 Monoclonal Antibody Mouse Human Non
FGF2-01H Active Recombinant Heat Stable Human FGF2 Protein, Animal Free Human cells Human 154 aa
FGF2-022H Active Recombinant Human FGF2 Protein E.coli Human Non 143-288 a.a.
FGF2-039H Recombinant Human FGF2 Protein E.coli Human 822
FGF2-044H Active Recombinant Human FGF2 Protein E.coli Human 144-288 a.a.
Fgf2-059M Recombinant Mouse Fgf2 Protein E.coli Mouse
Fgf2-060M Active Recombinant Mouse Fgf2 Protein E.coli Mouse 11-154 a.a.
Fgf2-061M Active Recombinant Mouse Fgf2 Protein E.coli Mouse
Fgf2-062M Recombinant Mouse Fgf2 Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK
FGF2-06B Recombinant Bovine/Porcine FGF2 Protein E.coli Bovine/Porcine 145 aa
FGF2-07B Recombinant Bovine/Porcine FGF2 Protein E.coli Bovine/Porcine 154 aa
fgf2-08Z Recombinant Zebrafish fgf2 Protein E.coli Zebrafish
FGF2-09H Recombinant Human FGF2 Protein E.coli Human 145 aa
FGF2-105H Recombinant Human Basic Fibroblast Growth Factor (rDNA derived) Reference standard E.coli Human Non
FGF2-108HG Active GMP Recombinant Human FGF2 Protein E.coli Human Non 143-288 a.a.
FGF2-10H Recombinant Human FGF2 Protein E.coli Human 154 aa
FGF2-122H Recombinant Human FGF2 Protein E.coli Human
FGF2-123H Recombinant Human FGF2 Protein E.coli Human 1-155 a.a.
FGF2-12B Recombinant Bovine FGF2 Protein E.coli Bovine Non
FGF2-130H Recombinant Human FGF2 Protein E.coli Human 132-288 a.a.
FGF2-133H Recombinant Human FGF2 Protein E.coli Human Pro143-Ser288
FGF2-1380H Recombinant Human FGF2 protein, MBP&His-Avi-tagged, Biotinylated E.coli Human His&MBP&Avi 143-288aa
Fgf2-13M Recombinant Mouse Fgf2 Protein E.coli Mouse
FGF2-1486H Recombinant Human FGF2 Protein, His-tagged E.coli Human His Pro10-Ser155
FGF2-1487H Recombinant Human FGF2 Protein, His-tagged E.coli Human His Pro143-Ser288
FGF2-1488H Recombinant Human FGF2 Protein, His-tagged E.coli Human His Pro143-Ser288
Fgf2-1489R Recombinant Rat Fgf2 Protein, His-tagged E.coli Rat His Pro10-Ser154
FGF2-14H Active Recombinant Human FGF2 Protein E.coli Human 154 aa
FGF2-155H Recombinant Human FGF2 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK
FGF2-15H Active Recombinant Human FGF2 Protein, Pre-aliquoted E.coli Human Pro143-Ser288
FGF2-16H Active Recombinant Human FGF2 Protein, Animal Free Human cells Human 154 aa
FGF2-178HG Active GMP Recombinant Human FGF2 protein CHO Human
FGF2-17H Active Recombinant Human FGF2 Protein (Formulation II-Carrier-Ready-to-Use, 134-288, 154 amino acid) E.coli Human 134-288, 154 amino acid
FGF2-1967R Recombinant Rat FGF2 Protein E.coli Rat Non
FGF2-1968M Recombinant Mouse FGF2 Protein E.coli Mouse Non
FGF2-1988R Recombinant Rat FGF2 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
FGF2-1988R-B Recombinant Rat FGF2 Protein Pre-coupled Magnetic Beads HEK293 Rat
FGF2-20H Active Recombinant Human FGF2 Protein (Formulation I- Animal Free-Lyophilized, 134-288, 154 amino acid) E.coli Human 134-288, 154 amino acid
FGF2-2120H Recombinant Human FGF2 protein, Avi & His-tagged, Biotinylated E.coli Human His&Avi Pro 143 - Ser 288
FGF2-2185C Recombinant Cattle FGF2 Protein, His-tagged E.coli Cattle His Pro10-Ser155
FGF2-2186C Recombinant Cattle FGF2 Protein, His-tagged E.coli Cattle His Phe26-Ser155 (Accession # P03969)
FGF2-21H Active Recombinant Human FGF2 Protein (Formulation I- Animal Free-Ready-to-Use, 134-288, 154 amino acid) E.coli Human 134-288, 154 amino acid
FGF2-23H Active Recombinant Human FGF2 Protein (Formulation I- Carrier Free-Ready-to-Use, 134-288, 154 amino acid) E.coli Human 134-288, 154 amino acid
FGF2-24H Active Recombinant Human FGF2 Protein (Formulation II-Carrier-Lyophilized, 134-288, 154 amino acid) E.coli Human 134-288, 154 amino acid
FGF2-25H Active Recombinant Human FGF2 Protein (Formulation I- Carrier Free-Lyophilized, 134-288, 154 amino acid) E.coli Human 134-288, 154 amino acid
Fgf2-25M Active Recombinant Mouse Fgf2 Protein (Ala11-Ser154), N-His tagged, Animal-free, Carrier-free E.coli Mouse His Ala11-Ser154
FGF2-26551TH Native Human FGF2 E.coli Human Non
FGF2-28HG Recombinant Human FGF2 Protein, GMP Grade, Animal-Free E.coli Human
FGF2-2910H Recombinant Human FGF2 protein, His-SUMO-tagged E.coli Human His&SUMO 143-288aa
FGF2-3017H Recombinant Human FGF2 Protein (Pro143-Ser288, Cys211Ser, Cys229Ser), N-SUMO tagged E.coli Human SUMO Pro143-Ser288, Cys211Ser, Cys229Ser
FGF2-3018H Recombinant Human FGF2 Protein (Pro143-Ser288), C-His tagged E.coli Human His Pro143-Ser288
FGF2-3232M Recombinant Mouse FGF2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
FGF2-3232M-B Recombinant Mouse FGF2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
FGF2-3244C Recombinant Chicken FGF2 protein, His-tagged E.coli Chicken His 13-158a.a.
FGF2-33HG Active Recombinant Human FGF2 Protein (Pro143-Ser288), GMP Grade, Animal-Free E.coli Human Pro143-Ser288
FGF2-353C Recombinant Chicken FGF2 protein, His-tagged E.coli Chicken His 13-158aa
Fgf2-397F Active Recombinant Rat Fgf2 Protein (146 aa) E.coli Rat 146
Fgf2-398F Active Recombinant Mouse Fgf2 Protein (146 aa) E.coli Mouse 146
FGF2-399F Active Recombinant Bovine FGF2 Protein (146 aa) E.coli Bovine 146
FGF2-400F Active Recombinant Human FGF2 Protein (154 aa) E.coli Human 154
FGF2-401F Active Recombinant Human FGF2 Protein (146 aa) E.coli Human 146
Fgf2-4025M Recombinant Mouse Fgf2 Protein (Pro143-Ser288), C-His tagged E.coli Mouse His Pro143-Ser288
FGF2-402F Active Recombinant Human FGF2 Protein (145 aa) E.coli Human 145
FGF2-4345HG GMP Recombinant Human FGF2 protein E.coli Human Non 147
FGF2-4422B Recombinant Bovine FGF2 protein, His-tagged Yeast Bovine His 10-155aa
Fgf2-5230M Recombinant Mouse Fgf2 protein, His-tagged E.coli Mouse His 10-154aa
FGF2-5403H Recombinant Human FGF2 protein, His-tagged Yeast Human His 143-288aa
Fgf2-5419M Recombinant Mouse Fgf2 Protein (Met1-Ser154) E.coli Mouse Non Met1-Ser154
FGF2-543H Active Recombinant Human FGF2 Protein E.coli Human Non
Fgf2-543M Recombinant Mouse Fgf2 protein, His-tagged Yeast Mouse His 10-155aa
Fgf2-544M Active Recombinant Mouse Fgf2 Protein E.coli Mouse Non
FGF2-5632C Recombinant Chicken FGF2 protein, His-tagged Yeast Chicken His 13-158aa
FGF2-57H Recombinant Human fibroblast growth factor 2 (basic) Protein, HA tagged Yeast Human HA
Fgf2-595R Active Recombinant Rat Fgf2 Protein E.coli Rat Non
FGF2-6739C Recombinant Chicken FGF2 protein, His-tagged E.coli Chicken His Phe29~Gly143
FGF2-6755R Recombinant Rabbit FGF2 protein, His-SUMO-tagged E.coli Rabbit N-His-SUMO 1-137aa
Fgf2-6841R Recombinant Rat Fgf2 Protein (Ala11-Ser154) E.coli Rat Non Ala11-Ser154
Fgf2-7206M Active Recombinant Mouse Fgf2 Protein E.coli Mouse
FGF2-7575C Recombinant Chicken FGF2 protein, His&Myc-tagged E.coli Chicken N-His&C-Myc 13-158aa
FGF2-77H Recombinant Active Human FGF2 Protein, His-tagged(N-ter) E.coli Human His
FGF2-78P Recombinant Active Pig FGF2 Protein, His-tagged(N-ter) E.coli Pig His
Fgf2-79M Recombinant Active Mouse FGF2 Protein, His-tagged(N-ter) E.coli Mouse His
FGF2-81H Active Recombinant Human FGF2 Protein E.coli Human
FGF2-82H Active Recombinant Human FGF2 Protein E.coli Human
FGF2-83M Active Recombinant Mouse FGF2 Protein E.coli Mouse
FGF2-84R Active Recombinant Rat FGF2 Protein E.coli Rat
FGF2-929P Recombinant Pig FGF2 Protein, His-tagged E.coli Pig His Pro10-Ser154
FGF2-94H Active Recombinant Human FGF2 Protein (Ala135-Ser288), N-His tagged, Animal-free, Carrier-free E.coli Human His Ala135-Ser288
FGF2-9685H Recombinant Human FGF2 protein, His-tagged E. coli Human His 170aa(including fusion tag)

    Involved Pathway

    FGF2 involved in several pathways and played different roles in them. We selected most pathways FGF2 participated on our site, such as MAPK signaling pathway,Ras signaling pathway,Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway FLNB,RAP1AA,NTF3,FGF14,PDGFAB,FGF17,MAP2K6,TRAF6,CACNA1D,MAPKAPK5
    Melanoma FGF11,MET,NRAS,FGF13,MAPK1,MAP2K1,FGF21,PIK3R2,PDGFRB,MAPK3
    Rap signaling pathway KRAS,ITGAM,RAPGEF5,GNAS,FGF17,FGF1,HRAS,ITGB2L,PARD6A,RAPGEF1
    Ras signaling pathway GNB2,GNG3,PRKACB,BRAP,FIGF,Fasl,TBK1,MAPK10,PLA2G2F,PLCG1
    Pathways in cancer CCND1,PAX8,APC2,PTGS2,LAMB1,LAMA1,ITGB1,AGTR1A,EGLN1,ARHGEF1
    PIK-Akt signaling pathway LPAR2,PIK3R5,IFNA8,FGF18,PKN1,RXRA,GYS2,IL7R,FGF20,OSMR
    Proteoglycans in cancer MMP9,PIK3R2,MAPK12,MMP2,MAPK3,HRAS,WNT10B,PTCH1,PIK3CG,WNT4
    Regulation of Actin Cytoskeleton F2,ROCK1,ITGA6,CHRM5B,SCINLB,PDGFRB,RAF1B,ITGB3,GNA13A,PDGFAA
    Signaling pathways regulating pluripotency of stem cells PCGF2,PIK3CA,PIK3CB,FGFR1,AXIN2,PIK3CG,FZD1,MAPK3,WNT1,ID3

    Protein Function

    FGF2 has several biochemical functions, for example, chemoattractant activity,cytokine activity,fibroblast growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF2 itself. We selected most functions FGF2 had, and list some proteins which have the same functions with FGF2. You can find most of the proteins on our site.

    Function Related Protein
    heparin binding PCOLCE2,FGFRL1,CYR61L1,NRP1A,ANG,FGF10,COL20A1,PTCH1,CCL5,PTN
    cytokine activity GM13288,IL36A,TNFSF15,LFT2,TGFB1A,AIMP1,IFNW1,HMGB1A,IL1RN,IFNA8
    chemoattractant activity PDGFB,SCG2,VEGFB,LGALS3,CXCL12,VEGFA,NTF3,CCL3,FGF8,CCL16
    ligand-dependent nuclear receptor transcription coactivator activity WDR77,ZMIZ2,PPRC1,CCAR1,SLC30A9,CARM1,TSG101,MED24,KDM1A,CALCOCO1
    growth factor activity TGFA,FGF20B,NRG2,EREG,TGFB1A,CNTF,IL10,FGF18,CXCL12,VEGFA
    fibroblast growth factor receptor binding FGF20B,FGF3,FGF10B,FGF18A,Fgf15,FGF10A,FGF16,KLB,FGF21,FGF1A
    protein binding NXT1,RABAC1,MTAP1B,SOX15,USP33,ADCY6,KRIT1,NR1I2,ESD,LRRC47

    Interacting Protein

    FGF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF2.

    FGFR1;FGFR2;FGFBP1;chondroitin sulfate;ssr;DCN;FGFR1;FGFR2;q6dtl8_bovin;ANOS1

    FGF2 Related Signal Pathway

    Resources

    Gene Families

    Growth Factors

    Research Area

    Cancer Drug Targets
    FGF Family
    Angiogenic Activator
    Fibroblast Growth Factor (FGF)
    Rheumatoid arthritis Therapeutic Targets
    Glioma Biomarkers
    Medulloblastoma Biomarkers
    Melanoma Biomarkers
    Angiogenic Activator in Cancer

    References

    • Correa, D; Somoza, RA; et al. Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation. OSTEOARTHRITIS AND CARTILAGE 23:443-453(2015).
    • Bohnsack, RN; Warejcka, DJ; et al. Expression of Insulin-Like Growth Factor 2 Receptor in Corneal Keratocytes During Differentiation and in Response to Wound Healing. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:7697-7708(2014).

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