CD79A
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Official Full Name
CD79a molecule, immunoglobulin-associated alpha -
Overview
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. -
Synonyms
CD79A;CD79a molecule, immunoglobulin-associated alpha;CD79A antigen (immunoglobulin associated alpha) , IGA;B-cell antigen receptor complex-associated protein alpha chain;MB 1;ig-alpha;MB-1 membrane glycoprotein;surface IgM-associated protein;CD79
Recombinant Proteins
- Human
- Mouse
- Cattle
- Cynomolgus
- Dog
- Mus musculus
- Bovine
- E.coli
- HEK293
- Human Cell
- Mammalian Cell
- Wheat Germ
- Human Cells
- Insect Cell
- Mammalian cells
- Mouse
- E.coli expression system
- GST
- rFc
- Fc
- His&Flag&StrepII
- His
- StrepII
- Non
- His&Flag
- His&T7
- His&Fc&Avi
- Flag
- PerCP&Cy5.5
Involved Pathway
CD79A involved in several pathways and played different roles in them. We selected most pathways CD79A participated on our site, such as B cell receptor signaling pathway,Primary i,nodeficiency, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD79A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| B Cell Receptor Signaling Pathway | PIK3R3,RAC1,PIK3CD,CARD11, Cd79b,SYK,NRAS,MAP2K1,ARPC3,ACTR3 |
| nodeficiency | CD3E,BTK,TAP2,AIRE,ICOS,CD19,RAG1,CD8B1,RFXAP,CD4 |
| Primary i | CD8B1,RFX5,CD8A,AIRE, Cd79b,ORAI1,RAG2,Cd79a,RFXAP,BLNK |
Protein Function
CD79A has several biochemical functions, for example, protein binding,transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD79A itself. We selected most functions CD79A had, and list some proteins which have the same functions with CD79A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RGP1,ZKSCAN1,C19orf80,L3MBTL3,FCHO2,TUBB4A,CCDC93,GAST,DPH1,KIF2A |
| transmembrane signaling receptor activity | DARC,TLR6,P2RX5,TLR2-2,GLP1R,CD97,NPR2,FZD7B,FZD8A,CD3D |
Interacting Protein
CD79A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD79A here. Most of them are supplied by our site. Hope this information will be useful for your research of CD79A.
FATE1;FN1
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References
- Chang, CH; Wang, Y; et al. Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells. MABS 7:199-211(2015).
- Chung, TH; Kim, HJ; et al. Multicentric epitheliotropic T-cell lymphoma in an African hedgehog (Atelerix albiventris). VETERINARY CLINICAL PATHOLOGY 43:601-604(2014).
