CD70

  • Official Full Name

    Cd70 CD70 antigen

  • Synonyms

    CD70;CD70 antigen;CD27-L;CD27 ligand;Ki-24 antigen;tumor necrosis factor ligand superfamily member 7;tumor necrosis factor (ligand) superfamily, member 7;Cd27l;CD27LG;Tnfsf7

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • Cynomolgus
  • Rhesus macaque
  • Mus musculus
  • HEK293
  • CHO
  • Wheat Germ
  • Human Cell
  • Mammalian Cell
  • Insect Cell
  • E.coli
  • Human cells
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian cells
  • Yeast
  • E.coli expression system
  • His
  • Fc
  • mFc
  • His&Flag
  • lFc
  • mIgG2a
  • rFC
  • Fc&Avi
  • HA
  • N-His-Flag
  • Non
  • His&Flag&StrepII
  • GST
  • hIgG4
  • His&GST
  • His&Fc&Avi
  • Flag
  • Myc&DDK
  • His&FLAG&Avi
  • His&Avi
  • His&Fc
  • His&mFc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CD70-196H Recombinant Human CD70 protein, His-tagged HEK293 Human His Leu50-Pro193
CD70-639 Recombinant Human CD70 protein, hFc-tagged HEK293 Human Fc Gln39-Pro193
Cd70-8730R Active Recombinant Rat Cd70 protein, hFc-tagged HEK293 Rat Fc 46-195 a.a.
Cd70-8731R Active Recombinant Rat Cd70 protein, His-tagged HEK293 Rat His Gln46-Pro195
Cd70-972M Active Recombinant Mouse Cd70 protein(Gln47-Pro159), mFc-tagged HEK293 Mouse mFc Gln47-Pro159
CD70-089H Recombinant Human CD70 protein, His-Flag-tagged HEK293 Human His&Flag It contains Gln50-Pro193 Trimer.
CD70-105C Recombinant Cynomolgus CD70 protein, His-tagged HEK293 Cynomolgus His Gln39-Pro194
CD70-328H Active Recombinant Human CD70 protein, lFc-tagged HEK293 Human lFc Ser 52 - Pro 193
CD70-329M Recombinant Mouse CD70 protein (active trimer)(HPLC-verified), His-tagged HEK293 Mouse His 149
CD70-330M Recombinant Mouse CD70 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse mIgG2a 149
CD70-437H Recombinant Human CD70 Protein (Gln39-Pro193), RIgG Fc-tagged HEK293 Human rFC Gln39-Pro193
CD70-639AF488 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Human Fc 413
CD70-639AF555 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Human Fc 413
CD70-639AF647 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Human Fc 413
CD70-639F Recombinant Human CD70 Protein, Fc-tagged, FITC conjugated HEK293 Human Fc 413
Cd70-8730RAF488 Recombinant Rat Cd70 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Rat Fc 410
Cd70-8730RAF555 Recombinant Rat Cd70 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Rat Fc 410
Cd70-8730RAF647 Recombinant Rat Cd70 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Rat Fc 410
Cd70-8730RF Recombinant Rat Cd70 Protein, Fc-tagged, FITC conjugated HEK293 Rat Fc 410
Cd70-8731RAF488 Recombinant Rat Cd70 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 Rat His 170
Cd70-8731RAF555 Recombinant Rat Cd70 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 Rat His 170
Cd70-8731RAF647 Recombinant Rat Cd70 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 Rat His 170
Cd70-8731RF Recombinant Rat Cd70 Protein, His-tagged, FITC conjugated HEK293 Rat His 170
CD70-891HA Recombinant Human CD70 protein, Fc-tagged, APC labeled HEK293 Human Fc
CD70-891HAF488 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Human Fc 39-193 a.a.
CD70-891HAF555 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Human Fc 39-193 a.a.
CD70-891HAF647 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Human Fc 39-193 a.a.
CD70-891HF Recombinant Human CD70 Protein, Fc-tagged, FITC conjugated HEK293 Human Fc 39-193 a.a.
CD70-892H Active Recombinant Human CD70 protein, hFc&Avi-tagged, Biotinylated HEK293 Human Fc&Avi 39-193 a.a.
Cd70-972MAF488 Recombinant Mouse Cd70 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Mouse Fc 385
Cd70-972MAF555 Recombinant Mouse Cd70 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Mouse Fc 385
Cd70-972MAF647 Recombinant Mouse Cd70 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Mouse Fc 385
Cd70-972MF Recombinant Mouse Cd70 Protein, Fc-tagged, FITC conjugated HEK293 Mouse Fc 385
CD70-116H Active Recombinant Human CD70, His-tagged CHO Human His
CD70-218H Active Recombinant Human CD70 Protein, HA/GCN4-IZ-tagged HEK293 Human HA 39-193 a.a.
CD70-001H Recombinant Human CD70 molecule Protein, His tagged HEK293 Human His 45-193 aa
CD70-434H Recombinant Human CD70 protein, His-Flag-tagged HEK293 Human N-His-Flag Gln45-Pro193
CD70-5764H Recombinant Human CD70 protein, His-tagged, Biotinylated(Primary Amine Labeling) HEK293 Human His Leu50-Pro193
CD70-639P Active Recombinant Human CD70 protein, Fc-tagged, R-PE labeled HEK293 Human Fc Gln 39-Pro 193
CD70-0848H Recombinant Human CD70 Protein Wheat Germ Human Non
CD70-0849H Recombinant Human CD70 Protein, His-Flag-StrepII-Tagged Human Cell Human His&Flag&StrepII 52-193 a.a.
CD70-0851H Recombinant Human CD70 Protein, GST-Tagged Wheat Germ Human GST
CD70-1804R Recombinant Rhesus Monkey CD70 Protein HEK293 Rhesus macaque Non 38-194 a.a.
CD70-1805R Recombinant Rhesus Monkey CD70 Protein, hIgG1-tagged HEK293 Rhesus macaque Fc 38-194 a.a.
CD70-1806R Recombinant Rhesus Monkey CD70 Protein, hIgG4-tagged HEK293 Rhesus macaque hIgG4 38-194 a.a.
CD70-3105M Recombinant Mouse CD70 Protein Mammalian Cell Mouse His
CD70-56H Recombinant Human CD70 protein, His-tagged Insect Cell Human His
CD70-6722H Recombinant Human CD70 protein, His & GST-tagged E.coli Human His&GST Gln47~Val191
Cd70-6723M Recombinant Mouse Cd70 protein, His-tagged E.coli Mouse His Leu64~Trp192
CD70-891H Recombinant Human CD70 Protein, Fc-tagged HEK293 Human Fc 39-193 a.a.
CD70-1303RCL Recombinant Rat CD70 cell lysate Human Cell Rat Non
CD70-2710HCL Recombinant Human CD70 cell lysate Human Cell Human Non
CD70-01H Recombinant Rhesus Monkey CD70 Protein, his-tagged HEK293 Rhesus macaque His 157
CD70-038H Recombinant Human CD70 Protein, Leu50-Pro193, N-His tagged, Biotinylated HEK293 Human His Leu50-Pro193
CD70-072H Active Recombinant Human CD70 Protein, His-Flag-tagged HEK293 Human His&Flag Ser52-Pro193
CD70-073H Active Recombinant Human CD70, hFc-tagged HEK293 Human Fc Ser52-Pro193
CD70-1467M Recombinant Mouse CD70 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
CD70-1467M-B Recombinant Mouse CD70 Protein Pre-coupled Magnetic Beads HEK293 Mouse
CD70-151H Recombinant Human CD70 Protein, DYKDDDDK-tagged Human cells Human Flag
Cd70-2065M Recombinant Mouse Cd70 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
CD70-206H Recombinant Human CD70 Protein, C-His-tagged E.coli Human His
CD70-2517H Recombinant Human CD70 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
CD70-2985H Active Recombinant Human CD70 protein, His-Flag-tagged, FITC-Labeled HEK293 Human His&Flag Ser 52-Pro 193
CD70-2986H Active Recombinant Human CD70 protein, His-Avi-Flag-tagged, Biotinylated HEK293 Human His&FLAG&Avi Ser 52-Pro 193
CD70-2987M Active Recombinant Mouse CD70 protein, His-Avi-tagged, Biotinylated HEK293 Mouse His&Avi Gln 47-Pro 195
CD70-2988M Active Recombinant Mouse CD70 protein, His-tagged HEK293 Mouse His Gln 47-Pro 195
CD70-2989M Active Recombinant Mouse CD70 protein, mFc-tagged HEK293 Mouse mFc Gln 47-Pro 195
CD70-3030HF Recombinant Full Length Human CD70 Protein In Vitro Cell Free System Human Full L. 392 amino acids
CD70-3055HF Recombinant Full Length Human CD70 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 193 amino acids
CD70-3100H Recombinant Human CD70 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
CD70-324H Active Recombinant Human CD70 Protein (Gln39-Pro193), N-His tagged, Animal-free, Carrier-free E.coli Human His Gln39-Pro193
CD70-328HG Active GMP Recombinant Human CD70 protein HEK293 Human DNA sequence encoding Human CD27 Ligand(UniProtKB/Swiss-Prot: P32970.2) was expressed with His tag at the C-terminal.
CD70-375HFL Active Recombinant Full Length Human CD70 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
CD70-435H Recombinant Human CD70(Gln45-Pro193) Protein, C-mFc-tagged HEK293 Human mFc 45-193 a.a.
CD70-436H Recombinant Human CD70 Protein (Gln39-Pro193), MIgG1 Fc-tagged HEK293 Human mFc Gln39-Pro193
CD70-514H Recombinant Human CD70 Protein (Gln39-Pro193), N-hFc and C-6×His-tagged HEK293 Human His&Fc Gln39-Pro193
CD70-515H Recombinant Human CD70 Protein (Gln39-Pro193), N-mFc and C-6×His-tagged HEK293 Human His&mFc Gln39-Pro193
CD70-5365H Recombinant Human CD70 Protein (Gln39-Pro193), N-Fc tagged Mammalian cells Human Fc Gln39-Pro193
CD70-5366H Recombinant Human CD70 Protein (Gln39-Pro193), N-His tagged Mammalian cells Human His Gln39-Pro193
CD70-5373H Recombinant Human CD70 protein, His-tagged Yeast Human His 39-193
CD70-545H Recombinant Human CD70 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
CD70-545H-B Recombinant Human CD70 Protein Pre-coupled Magnetic Beads HEK293 Human
CD70-623H Recombinant Human CD70 Protein, Fc-tagged HEK293 Human Fc 193
CD70-639A Recombinant Human CD70 protein, Fc-tagged, APC labeled HEK293 Human Fc
Cd70-8730RA Recombinant Rat Cd70 protein, Fc-tagged, APC labeled HEK293 Rat Fc
Cd70-8730RP Recombinant Rat Cd70 protein, Fc-tagged, R-PE labeled HEK293 Rat Fc
Cd70-87M Active Recombinant Mouse Cd70 Protein (Gln47-Pro195), N-His tagged, Animal-free, Carrier-free E.coli Mouse His Gln47-Pro195
CD70-891HP Recombinant Human CD70 protein, Fc-tagged, R-PE labeled HEK293 Human Fc
Cd70-972MA Recombinant Mouse Cd70 protein, Fc-tagged, APC labeled HEK293 Mouse Fc
Cd70-972MP Recombinant Mouse Cd70 protein, Fc-tagged, R-PE labeled HEK293 Mouse Fc
RFL17124MF Recombinant Full Length Mouse Cd70 Antigen(Cd70) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-195)

    Involved Pathway

    CD70 involved in several pathways and played different roles in them. We selected most pathways CD70 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD70 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IL13,TGFBR1A,IL20,IL10,VEGFA,IL18R1,VEGFC,CCR3,NGFRB,CCL5

    Protein Function

    CD70 has several biochemical functions, for example, cytokine activity,protease binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD70 itself. We selected most functions CD70 had, and list some proteins which have the same functions with CD70. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TCERG1,ATP6V1E1,BUB3,STATH,TXN2,EYA1,UBE2K,FBXO45,SNX7,MAP3K1
    tumor necrosis factor receptor binding TRAF1,TNFSF8,TRAP1,TNF,TRIM37,TNFSF4,EDA,LTB,TNFSF12,TNFSF10L3
    protease binding CRADD,FADD,OS9,BRCA2,FURIN,PANX1,CHL1,TP53,TIMP2,TRP53
    cytokine activity Kitl,GDF15,Ifnz,CTF1,IFNK,FGF2,IL17B,RNF207B,WNT5A,IFNPHI1
    receptor binding PTK2B,TAC3,DECR2,EPB49,TNFSF10,ICOSLG,FGF8A,INSL3,TNFSF4,TRDN

    Interacting Protein

    CD70 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD70 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD70.

    Resources

    Gene Families

    Cytokines

    Research Area

    Cancer Drug Targets
    Co-stimulatory TNF Superfamily Molecules
    gamma delta T Cells
    CD Antigen (Helper T Cells)
    Tumor Necrosis Factor (TNF)
    Co-stimulatory Molecules
    CAR-T Cell Therapy Targets
    Immune Checkpoints

    References

    • Convers, KD; Kariuki, BM; et al. Decreased CD5(-)CD19(+)CD27(+)CD43(+)CD70(-) B-Cell Subpopulation in Children with Specific Antibody Deficiency. PEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY 28:27-31(2015).
    • Tannir, NM; Forero-Torres, A; et al. Phase I dose-escalation study of SGN-75 in patients with CD70-positive relapsed/refractory non-Hodgkin lymphoma or metastatic renal cell carcinoma. INVESTIGATIONAL NEW DRUGS 32:1246-1257(2014).

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