Pgf
-
Official Full Name
placental growth factor -
Overview
This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011] -
Synonyms
PGF;placental growth factor;PGFL;PLGF;PlGF-2;D12S1900;SHGC-10760;placenta growth factor;placental growth factor, vascular endothelial growth factor-related protein
Recombinant Proteins
- Mouse
- Human
- Cynomolgus
- Rat
- Rhesus macaque
- Human Cell
- Insect Cells
- E.coli
- HEK293
- CHO
- C-His
- HEK293T
- Sf21 Insect Cell
- Mammalian Cell
- Insect Cell
- HEK293 cells
- HEK293F
- Mamanlian cells
- Mammalian cells
- His
- Non
- mFc
- StrepII
- His&GST
- Fc
- GST
- His&Fc
- His&SUMO
- His&Fc&Avi
- Flag
Involved Pathway
Pgf involved in several pathways and played different roles in them. We selected most pathways Pgf participated on our site, such as Ras signaling pathway,Rap signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pgf were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rap signaling pathway | FGF10,PRKCI,Kitl,FGF11,FYB,RAC2,MRAS,TLN1,PARD3,CALM1 |
| Ras signaling pathway | GNB3,FGF9,RASA1,PAK2,STK4,Kitl,FLT1,PLA2G4C,PAK6,FGF20 |
| Pathways in cancer | FGF13,FGFR1,GLI3,WNT6,CDH1,BIRC8,GNB4,MSH3,FZD7,NOS2 |
| PIK-Akt signaling pathway | PTK2,GNB1,FGF2,GNG2,STK11,IBSP,VEGFA,FGF20,PDGFA,IFNA1 |
| Focal adhesion | ACTB2,COL5A1,MAPK8B,ACTB,PDPK1B,AKT2,COL2A1B,MYLPFB,PDGFB,PDGFC |
Protein Function
Pgf has several biochemical functions, for example, growth factor activity,heparin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Pgf itself. We selected most functions Pgf had, and list some proteins which have the same functions with Pgf. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| heparin binding | CXCL6,FGF10,ITGAM,CXCL13,ADAMTS3,SERPINE2,APOA5,PDCD5,VEGFAA,SLIT1 |
| growth factor activity | TGFB3,CLCF1,TGFB2,FGF7,VEGFA,PDGFA,REG1A,FGF21,CDNF,FGF12A |
| protein binding | FAM128B,HMG20A,AMELX,KRT20,ZNF543,EIF2B2,CHMP4B,KCNH2,CDC27,N4BP2L2 |
Interacting Protein
Pgf has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pgf here. Most of them are supplied by our site. Hope this information will be useful for your research of Pgf.
FLT1;VEGFA
Resources
Research Area
VEGF FamilyAngiogenic Activator
Epithelial Cell Markers and Intracellular Molecules
Vascular Endothelial Growth Factors (VEGFs)
Angiogenic Activator in Cancer
Related Services
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References
- Hashiba, K; Sano, M; et al. Galectin-3 Contributes to Luteolysis by Binding to Beta 1 Integrin in the Bovine Corpus Luteum. BIOLOGY OF REPRODUCTION 91:-(2014).
- Shida, T; Nozawa, T; et al. Fluvastatin-induced reduction of oxidative stress ameliorates diabetic cardiomyopathy in association with improving coronary microvasculature. HEART AND VESSELS 29:532-541(2014).
