Recombinant Mouse Placental Growth Factor

• Cat.No.: Pgf-606M
• Product Overview: Recombinant human Pgf is a 32.6 kDa homodimeric protein consisting of two 142 amino acid polypeptide chains.

Specification

• Species: Mouse
• Source: E.coli
• Tag: Non
• Description: Pgf is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. Pgf is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration.
• Biological Activity: Determined by its ability to chemoattract human monocytes of using a concentration range of 0.5-10 ng/ml.
• Molecular Weight: 32.6 kDa
• Form: Sterile filtered and lyophilized without additives.
• Endotoxin Level: <0.1 ng/μg
• Appearance: Lyophilized protein
• Reconstitution: Reconstitute the protein in sterile 20 mM acetic acid to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffer.
• Purity: >98% by SDS-PAGE and ≥95% by HPLC
• Storage: The lyophilized protein is best-stored desiccated below 0°C. Reconstituted protein should be stored at working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA). Prevent freeze/thaw cycles.

Gene Information

• Gene Name: Pgf placental growth factor [ Mus musculus ]
• Official Symbol: Pgf
• Synonyms: Pgf; placental growth factor; PIGF; Plgf; AI854365; placenta growth factor
• Gene ID: 18654
• mRNA Refseq: NM_008827
• Protein Refseq: NP_032853
• UniProt ID: P49764
• Chromosome Location: 12 D
• Pathway: Bladder cancer; Focal Adhesion; Focal adhesion; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; Rheumatoid arthritis; Signaling by VEGF; VEGF binds to VEGFR leading to receptor dimerization; VEGF ligand-receptor interactions; mTOR signaling pathway
• Function: growth factor activity; protein heterodimerization activity