Recombinant Human KL Protein, His&SUMO-tagged

• Cat.No.: KL-1071H
• Product Overview: Recombinant Human KL Protein (Phe765-Ser981) with His&SUMO tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&SUMO
• Protein Length: Phe765-Ser981
• Description: This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 39.2 kDa; Accurate Molecular Mass: 41 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: KL klotho [ Homo sapiens (human) ]
• Official Symbol: KL
• Synonyms: KL; klotho
• Gene ID: 9365
• mRNA Refseq: NM_004795
• Protein Refseq: NP_004786
• MIM: 604824
• UniProt ID: Q9UEF7