Recombinant Full Length Human ATOX1 Protein, with Cu (I)
| Cat.No. : | ATOX1-225H |
| Product Overview : | Recombinant full length Human Cu (I)-ATOX1 (aa 1-68) was expressed in E. coli. Binding of Cu (I) to the protein was confirmed by ICP. |
| Unit | |
| Price | |
| Qty |
- Specification
- Gene Information
- Related Products
- Download
| Product Overview : | Recombinant full length Human Cu (I)-ATOX1 (aa 1-68) was expressed in E. coli. Binding of Cu (I) to the protein was confirmed by ICP. |
| Description : | This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. |
| Source : | E. coli |
| Species : | Human |
| Form : | In 20 mM Phosphate buffer pH 7.0. |
| Molecular Mass : | 7.4 kDa |
| Protein length : | aa 1-68 |
| AA Sequence : | MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LIATLKKTGK TVSYLGLE |
| Purity : | >95% by SDS-PAGE. The protein was observed as a single band migrating at a molecular weight < 10 kDa. |
| Notes : | To avoid oxidation and leaking of the Cu(I) bound to the protein, keep and use the sample under inert atomosphere. |
| Storage : | Store at - 20 centigrade. The protein is stable at 4 centigrade for at least 2 weeks and at 25 centigrade for at least several hours. After initial deforst, aliquot product into individual tubes under inert atomosphere and refreeze at - 20 centigrade. Avoid repeated freeze/defrost cycles. Avoid exposition to air. |
| Concentration : | 1 mg/ml |
| Tag : | Non |
| Gene Name | ATOX1 ATX1 antioxidant protein 1 homolog (yeast) [ Homo sapiens ] |
| Official Symbol | ATOX1 |
| Synonyms | ATOX1; ATX1 antioxidant protein 1 homolog (yeast); ATX1 (antioxidant protein 1, yeast) homolog 1; copper transport protein ATOX1; HAH1; metal transport protein ATX1; ATX1; MGC138453; MGC138455; |
| Gene ID | 475 |
| mRNA Refseq | NM_004045 |
| Protein Refseq | NP_004036 |
| MIM | 602270 |
| UniProt ID | O00244 |
| Chromosome Location | 5q32 |
| Pathway | Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem; |
| Function | copper chaperone activity; copper ion binding; copper-dependent protein binding; metal ion binding; metallochaperone activity; |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All ATOX1 Products
Required fields are marked with *
My Review for All ATOX1 Products
Required fields are marked with *
0
Inquiry Basket
