Kdr

  • Official Full Name

    kinase insert domain receptor (a type III receptor tyrosine kinase)

  • Overview

    Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

  • Synonyms

    KDR;kinase insert domain receptor (a type III receptor tyrosine kinase);FLK1;CD309;VEGFR;VEGFR2;vascular endothelial growth factor receptor 2;soluble VEGFR2;fetal liver kinase 1;fetal liver kinase-1;protein-tyrosine kinase receptor Flk-1;tyrosine kinase growth factor receptor

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • Chicken
  • Zebrafish
  • Pig
  • Cynomolgus
  • Rhesus macaque
  • Mammalian Cells
  • Insect Cells
  • HEK293
  • E.coli
  • Sf9 Cells
  • Human Cells
  • His&Fc
  • Fc
  • His
  • His&Avi
  • His&GST
  • mFc
  • GST
  • Strep
  • Fc&Avi
  • Non
  • Flag
  • His&T7
  • Twin Strep
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
KDR-1697HAF488 Active Recombinant Human KDR Protein, Fc/His-tagged, Alexa Fluor 488 conjugated Mammalian Cells Human His&Fc
KDR-1697HAF555 Active Recombinant Human KDR Protein, Fc/His-tagged, Alexa Fluor 555 conjugated Mammalian Cells Human His&Fc
KDR-1697HAF647 Active Recombinant Human KDR Protein, Fc/His-tagged, Alexa Fluor 647 conjugated Mammalian Cells Human His&Fc
KDR-1697HF Active Recombinant Human KDR Protein, Fc/His-tagged, FITC conjugated Mammalian Cells Human His&Fc
Kdr-1786MAF488 Active Recombinant Mouse Kdr Protein, Fc/His-tagged, Alexa Fluor 488 conjugated Mammalian Cells Mouse His&Fc 1-762 a.a.
Kdr-1786MAF555 Active Recombinant Mouse Kdr Protein, Fc/His-tagged, Alexa Fluor 555 conjugated Mammalian Cells Mouse His&Fc 1-762 a.a.
Kdr-1786MAF647 Active Recombinant Mouse Kdr Protein, Fc/His-tagged, Alexa Fluor 647 conjugated Mammalian Cells Mouse His&Fc 1-762 a.a.
Kdr-1786MF Active Recombinant Mouse Kdr Protein, Fc/His-tagged, FITC conjugated Mammalian Cells Mouse His&Fc 1-762 a.a.
KDR-236HAF488 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 488 conjugated Mammalian Cells Human Fc
KDR-236HAF555 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 555 conjugated Mammalian Cells Human Fc
KDR-236HAF647 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 647 conjugated Mammalian Cells Human Fc
KDR-236HF Active Recombinant Human KDR Protein, Fc-tagged, FITC conjugated Mammalian Cells Human Fc
KDR-5442HAF488 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 488 conjugated Insect Cells Human Fc
KDR-5442HAF555 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 555 conjugated Insect Cells Human Fc
KDR-5442HAF647 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 647 conjugated Insect Cells Human Fc
KDR-5442HF Active Recombinant Human KDR Protein, Fc-tagged, FITC conjugated Insect Cells Human Fc
KDR-645HAF488 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Human Fc Met1-Lys327， 549
KDR-645HAF555 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Human Fc Met1-Lys327， 549
KDR-645HAF647 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Human Fc Met1-Lys327， 549
KDR-645HF Active Recombinant Human KDR Protein, Fc-tagged, FITC conjugated HEK293 Human Fc Met1-Lys327， 549
KDR-83HAF488 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 488 conjugated Insect Cells Human Fc
KDR-83HAF555 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 555 conjugated Insect Cells Human Fc
KDR-83HAF647 Active Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 647 conjugated Insect Cells Human Fc
KDR-83HF Active Recombinant Human KDR Protein, Fc-tagged, FITC conjugated Insect Cells Human Fc
KDR-1080RAF488 Recombinant Rat KDR Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 Rat His 752
KDR-1080RAF555 Recombinant Rat KDR Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 Rat His 752
KDR-1080RAF647 Recombinant Rat KDR Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 Rat His 752
KDR-1080RF Recombinant Rat KDR Protein, His-tagged, FITC conjugated HEK293 Rat His 752
KDR-2712H Recombinant Human KDR protein, His-tagged E.coli Human His 1158-1345 aa
KDR-31716THAF488 Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 488 conjugated Insect Cells Human Fc
KDR-31716THAF555 Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 555 conjugated Insect Cells Human Fc
KDR-31716THAF647 Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 647 conjugated Insect Cells Human Fc
KDR-31716THF Recombinant Human KDR Protein, Fc-tagged, FITC conjugated Insect Cells Human Fc
KDR-632H Recombinant Human KDR protein, His-Avi-tagged, Biotinylated HEK293 Human His&Avi Ala20-Glu764
KDR-643HAF488 Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Human Fc 979
KDR-643HAF555 Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Human Fc 979
KDR-643HAF647 Recombinant Human KDR Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Human Fc 979
KDR-643HF Recombinant Human KDR Protein, Fc-tagged, FITC conjugated HEK293 Human Fc 979
KDR-6966HAF488 Recombinant Human KDR Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 Human His 756
KDR-6966HAF555 Recombinant Human KDR Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 Human His 756
KDR-6966HAF647 Recombinant Human KDR Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 Human His 756
KDR-6966HF Recombinant Human KDR Protein, His-tagged, FITC conjugated HEK293 Human His 756
Kdr-7413MAF488 Recombinant Mouse Kdr Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Mouse Fc 984
Kdr-7413MAF555 Recombinant Mouse Kdr Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Mouse Fc 984
Kdr-7413MAF647 Recombinant Mouse Kdr Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Mouse Fc 984
Kdr-7413MF Recombinant Mouse Kdr Protein, Fc-tagged, FITC conjugated HEK293 Mouse Fc 984
KDR-7515HAF488 Recombinant Human KDR Protein, His/GST-tagged, Alexa Fluor 488 conjugated Insect Cells Human His&GST 787
KDR-7515HAF555 Recombinant Human KDR Protein, His/GST-tagged, Alexa Fluor 555 conjugated Insect Cells Human His&GST 787
KDR-7515HAF647 Recombinant Human KDR Protein, His/GST-tagged, Alexa Fluor 647 conjugated Insect Cells Human His&GST 787
KDR-7515HF Recombinant Human KDR Protein, His/GST-tagged, FITC conjugated Insect Cells Human His&GST 787
Kdr-8115MAF488 Recombinant Mouse Kdr Protein, mmFc-tagged, Alexa Fluor 488 conjugated HEK293 Mouse mFc Ala20-Glu762
Kdr-8115MAF555 Recombinant Mouse Kdr Protein, mmFc-tagged, Alexa Fluor 555 conjugated HEK293 Mouse mFc Ala20-Glu762
Kdr-8115MAF647 Recombinant Mouse Kdr Protein, mmFc-tagged, Alexa Fluor 647 conjugated HEK293 Mouse mFc Ala20-Glu762
Kdr-8115MF Recombinant Mouse Kdr Protein, mmFc-tagged, FITC conjugated HEK293 Mouse mFc Ala20-Glu762
KDR-8718RAF488 Recombinant Rat Kdr Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Rat Fc 982
KDR-8718RAF555 Recombinant Rat Kdr Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Rat Fc 982
KDR-8718RAF647 Recombinant Rat Kdr Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Rat Fc 982
KDR-8718RF Recombinant Rat Kdr Protein, Fc-tagged, FITC conjugated HEK293 Rat Fc 982
KDR-947MAF488 Recombinant Mouse KDR Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 Mouse His 754
KDR-947MAF555 Recombinant Mouse KDR Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 Mouse His 754
KDR-947MAF647 Recombinant Mouse KDR Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 Mouse His 754
KDR-947MF Recombinant Mouse KDR Protein, His-tagged, FITC conjugated HEK293 Mouse His 754
KDR-1421H Active Recombinant Human KDR, GST-tagged Sf9 Cells Human GST 789 aa-end
KDR-236H Active Recombinant Human KDR, Fc Chimera Mammalian Cells Human Fc
KDR-630H Active Recombinant Human KDR, His-tagged, Biotinylated Human Cells Human His 20-764 a.a.
KDR-631H Active Recombinant Human KDR, Fc-tagged, Biotinylated Human Cells Human Fc 20-764 a.a.
KDR-645H Active Recombinant Human KDR protein, Fc-tagged HEK293 Human Fc Met1-Lys327
KDR-6967H Active Recombinant Human KDR Protein, His & Avi-tagged, Biotinylated HEK293 Human His&Avi Ala 20 - Glu 764
KDR-6968H Active Recombinant Human KDR Protein, Strep-tagged HEK293 Human Strep 20-764 a.a.
KDR-051H Active Recombinant Human KDR protein, Fc/Avi-tagged, Biotinylated HEK293 Human Fc&Avi Ala20-Glu764
KDR-0643H Active Recombinant Human KDR Protein, hFc-tagged HEK293 Human Fc Asp120-Lys327
KDR-1378M Acitve Recombinant Mouse KDR protein(Met1-Glu762), His-tagged, Biotinylated HEK293 Mouse His Met1-Glu762
KDR-4657H Active Recombinant Human KDR Protein, His-tagged, Site-specific APC-Labeled HEK293 Human His Ala 20 - Glu 764
KDR-5143H Recombinant Human KDR protein, mFc-tagged HEK293 Human mFc Ala20-Glu764
KDR-1080R Recombinant Rat KDR Protein, His-tagged HEK293 Rat His 1-760 a.a.
KDR-1187C Recombinant Chicken KDR Mammalian Cells Chicken His
KDR-1263RCL Recombinant Human KDR HEK293 cell lysate HEK293 Human His Met 1-Glu 764
KDR-1619RCL Recombinant Human KDR HEK293 cell lysate HEK293 Human Fc Met 1-Glu 764
KDR-1697H Recombinant Human KDR, Fc-His Mammalian Cells Human His&Fc
Kdr-1786M Recombinant Mouse Kinase Insert Domain Protein Receptor, Fc-His Mammalian Cells Mouse Fc 1-762 a.a.
KDR-240H Recombinant Human KDR, C13&N15-labeled HEK293 Human Non 1-764 a.a.
KDR-3055Z Recombinant Zebrafish KDR Mammalian Cells Zebrafish His
KDR-31715TH Recombinant Human KDR, His-tagged Human His
KDR-31716TH Recombinant Human KDR, Fc-tagged Human Fc
KDR-31717TH Recombinant Human KDR Human Non 805-1356 a.a.
KDR-317H Recombinant Human Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase), His-tagged HEK293 Human His
KDR-3239R Recombinant Rat KDR Protein Mammalian Cells Rat His
KDR-340H Recombinant Human Kinase Insert Domain Receptor, GST-tagged, Active Sf9 Cells Human GST 789-end a.a.
KDR-387H Recombinant Human KDR Mammalian Cells Human His
KDR-511H Recombinant Human KDR protein, His-tagged HEK293 Human His Ala20~Glu764
KDR-5442H Recombinant Human Kinase Insert Domain Receptor (a type III receptor tyrosine kinase), Fc-tagged Insect Cells Human Fc
KDR-5443H Recombinant Human Kinase Insert Domain Receptor (a type III receptor tyrosine kinase), His-tagged Insect Cells Human His 789-1356 a.a.
KDR-5446H Recombinant Human Kinase Insert Domain Receptor (a type III receptor tyrosine kinase), GST-tagged Sf9 Cells Human GST 805-1356 a.a.
KDR-5447H Recombinant Human Kinase Insert Domain Receptor (a type III receptor tyrosine kinase) Insect Cells Human Non
KDR-58H Recombinant Human KDR protein, Flag-tagged, Biotinylated Insect Cells Human Flag 790-1356 a.a.
KDR-61H Recombinant Human KDR Insect Cells Human Non
KDR-643H Active Recombinant Human KDR protein, hFc-tagged HEK293 Human Fc 1-764 a.a.
KDR-6865H Recombinant Human KDR protein, His-tagged E.coli Human His Asn46~Thr320
Kdr-6866M Recombinant Mouse Kdr protein, His-tagged E.coli Mouse His Asn46~Thr322
KDR-6867P Recombinant Pig KDR protein, His & GST-tagged E.coli Pig His&GST Phe8~Val290
Kdr-6868R Recombinant Rat Kdr protein, His & T7-tagged E.coli Rat His&T7 Asn46~Thr320
KDR-6966H Recombinant Human KDR, His tagged Human Cells Human His 1-764 a.a.
Kdr-7413M Active Recombinant Mouse Kdr protein, hFc-tagged HEK293 Mouse Fc Met1-Glu762
KDR-7515H Active Recombinant Human KDR protein, His&GST-tagged Insect Cells Human His&GST Asp807-Val1356
KDR-83H Recombinant Human Kinase Insert Domain Receptor, 7 Domains,Fc-tagged Insect Cells Human Fc
KDR-84H Recombinant Human Kinase Insert Domain Receptor, 7 Domains Insect Cells Human Non
KDR-8718R Active Recombinant Rat KDR protein(Met1-Glu760), hFc-tagged HEK293 Rat Fc Met1-Glu760
KDR-8719R Recombinant Rat Kdr, His-tagged Human Cells Rat His 1-760 a.a.
KDR-947M Recombinant Mouse KDR Protein, His-tagged HEK293 Mouse His 1-762 a.a.
KDR-958H Recombinant Human KDR Protein, DDK-tagged Sf9 Cells Human Flag -20 a.a.
KDR-959H Recombinant Human KDR Protein, DDK-tagged Sf9 Cells Human Flag -834 a.a.
KDR-1520MCL Recombinant Mouse KDR cell lysate Human Cells Mouse Non
KDR-1769HCL Recombinant Human KDR cell lysate Human Cells Human Non
KDR-417HCL Recombinant Human KDR cell lysate Insect Cells Human Non
KDR-01H Recombinant Human KDR Protein (20-764aa), C-hIgG-His tagged Insect Cells Human His&Fc 20-764aa
KDR-066H Recombinant Human KDR Protein, His-tagged E.coli Human His Tyr 161-Cys 647
KDR-06H Recombinant Human KDR Protein (20-764aa), C-hIgG-His tagged Insect Cells Human His&Fc 20-764aa
KDR-070H Recombinant Human KDR Protein, His-tagged Human Cells Human His 120-320 a.a.
Kdr-071M Recombinant Mouse Kdr Protein, His-tagged Human Cells Mouse His 20-762 a.a.
KDR-0821H Active Recombinant Human KDR protein, Fc-tagged HEK293 Human Fc 20-764 a.a.
KDR-0822H Recombinant Human KDR protein, His-tagged, FITC-Labeled HEK293 Human His 20-764 a.a.
KDR-0823H Active Recombinant Human KDR protein, Twin-Strep-tagged HEK293 Human Twin Strep 20-764 a.a.
KDR-0824H Active Recombinant Human KDR protein, His-tagged HEK293 Human His 20-764 a.a.
KDR-102H Recombinant Human KDR Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
KDR-102H-B Recombinant Human KDR Protein Pre-coupled Magnetic Beads HEK293 Human
KDR-1049H Recombinant Human KDR protein(Met1-Lys327), hFc-tagged, Biotinylated HEK293 Human Fc Met1-Lys327
KDR-1084H Recombinant Human KDR protein(Met1-Lys327), His-tagged HEK293 Human His Met1-Lys327
KDR-1122C Recombinant Cynomolgus KDR Protein (Met1-Glu764), His-tagged HEK293 Cynomolgus His Met1-Glu764
KDR-1132H Recombinant Human KDR Protein (Ala20-Glu764), N-His tagged E.coli Human His Ala20-Glu764
KDR-1168H Recombinant Human KDR protein(Met1-Glu764), His-Avi-tagged, Biotinylated HEK293 Human His&Avi Met1-Glu764
KDR-1315H Recombinant Human KDR Protein (Q2-V1356), GST tagged Insect Cells Human GST Q2-V1356
KDR-1316H Recombinant Human KDR Protein (Q2-V1356), Tag Free Insect Cells Human Non Q2-V1356
KDR-1697HA Recombinant Human KDR protein, Fc-His-tagged, APC labeled Mammalian Cells Human His&Fc
KDR-1697HP Recombinant Human KDR protein, Fc-His-tagged, R-PE labeled Mammalian Cells Human His&Fc
Kdr-1786MA Recombinant Mouse Kdr protein, Fc-His-tagged, APC labeled Mammalian Cells Mouse His&Fc
Kdr-1786MP Recombinant Mouse Kdr protein, Fc-His-tagged, R-PE labeled Mammalian Cells Mouse His&Fc
KDR19697H Recombinant Human KDR (814-1171) Deletion (940-990 Protein Human
KDR-236HA Recombinant Human KDR protein, Fc-tagged, APC labeled Mammalian Cells Human Fc
KDR-236HP Recombinant Human KDR protein, Fc-tagged, R-PE labeled Mammalian Cells Human Fc
KDR-245M Recombinant Mouse KDR Protein, His-tagged Mammalian Cells Mouse His Ala20-Glu762
KDR-2742H Recombinant Human KDR protein(1201-1300 aa), C-His-tagged E.coli Human His 1201-1300 aa
KDR-2895R Recombinant Rat KDR Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
KDR-2895R-B Recombinant Rat KDR Protein Pre-coupled Magnetic Beads HEK293 Rat
KDR-3132H Recombinant Human KDR protein, GST-tagged E.coli Human GST 20-764aa
KDR-31716THA Recombinant Human KDR protein, Fc-tagged, APC labeled Insect Cells Human Fc
KDR-31716THP Recombinant Human KDR protein, Fc-tagged, R-PE labeled Insect Cells Human Fc
KDR-4331H Recombinant Human KDR Protein (Met1-Lys327), C-His tagged Mammalian Cells Human His Met1-Lys327
KDR-4332H Recombinant Human KDR Protein (Met1-Glu764), C-His tagged Mammalian Cells Human His Met1-Glu764
KDR-4656H Active Recombinant Human KDR Protein, His-tagged, Site-specific PE-Labeled HEK293 Human His Ala 20 - Glu 764
KDR-475H Recombinant Human KDR Protein, His-tagged HEK293 Human His 1356
KDR-476H Recombinant Human KDR Protein, Strep-tagged HEK293 Human Strep 1356
KDR-477R Recombinant Rhesus macaque KDR Protein, His-tagged HEK293 Rhesus macaque His 1356
KDR-5442HA Recombinant Human KDR protein, Fc-tagged, APC labeled Insect Cells Human Fc
KDR-5442HP Recombinant Human KDR protein, Fc-tagged, R-PE labeled Insect Cells Human Fc
KDR-564H Recombinant Human KDR Protein, C13 and N15 Labeled HEK293 Human 1356
KDR-643HA Recombinant Human KDR protein, Fc-tagged, APC labeled HEK293 Human Fc
KDR-643HP Recombinant Human KDR protein, Fc-tagged, R-PE labeled HEK293 Human Fc
KDR-645HA Recombinant Human KDR protein, Fc-tagged, APC labeled HEK293 Human Fc
KDR-645HP Recombinant Human KDR protein, Fc-tagged, R-PE labeled HEK293 Human Fc
KDR-666H Recombinant Human KDR Protein(Domain 2&3), His-tagged HEK293 Human His Asp120-Lys327
KDR-667H Recombinant Human KDR protein, His-Avi-tagged HEK293 Human His&Avi It contains Ala20-Glu764.
Kdr-7413MA Recombinant Mouse Kdr protein, Fc-tagged, APC labeled HEK293 Mouse Fc
Kdr-7413MP Recombinant Mouse Kdr protein, Fc-tagged, R-PE labeled HEK293 Mouse Fc
Kdr-7422M Active Recombinant Mouse Kdr Protein Insect Cells Mouse
Kdr-8115M Active Recombinant Mouse Kdr protein, mFc-tagged HEK293 Mouse mFc Ala 20 - Glu 762
Kdr-8115MA Recombinant Mouse Kdr protein, mFc-tagged, APC labeled HEK293 Mouse mFc
Kdr-8115MP Recombinant Mouse Kdr protein, mFc-tagged, R-PE labeled HEK293 Mouse mFc
KDR-8116R Active Recombinant Rhesus macaque KDR protein, His-tagged HEK293 Rhesus macaque His Ala 20 - Glu 764
Kdr-81M Recombinant Mouse Kdr Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
Kdr-81M-B Recombinant Mouse Kdr Protein Pre-coupled Magnetic Beads HEK293 Mouse
KDR-83HA Recombinant Human KDR 7 Domains protein, Fc-tagged, APC labeled Insect Cells Human Fc
KDR-83HP Recombinant Human KDR 7 Domains protein, Fc-tagged, R-PE labeled Insect Cells Human Fc
KDR-8718RA Recombinant Rat KDR protein, Fc-tagged, APC labeled HEK293 Rat Fc
KDR-8718RP Recombinant Rat KDR protein, Fc-tagged, R-PE labeled HEK293 Rat Fc
KDR8757H Recombinant Human KDR (806-1171) Deletion (940-990) Protein Human

    Involved Pathway

    Kdr involved in several pathways and played different roles in them. We selected most pathways Kdr participated on our site, such as Axon guidance,Cytokine-cytokine receptor interaction,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with Kdr were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance AP2S1,CFL2,PAK1,RAC3,ARPC2,DOCK1,PPP3CB,SCN2A,GFRA1,NETO2
    Focal adhesion CAV1,PDGFD,MAPK8A,IBSP,PTK2,TNR,PDGFRB,FLT4,TESK2,PAK6B
    Developmental Biology PAQR3A,WDR83,BNIP2,FRS3,DUSP6,GPC1A,EFNA3,PCSK6,RGMB,EFNA1B
    Id Signaling Pathway MYF6,ELK3,ACVRL1,MYOD1,PAX2,TCF12,IFI16,MYOG,TCF3B,MSC
    EPHA-mediated growth cone collapse EFNA3,EFNA1A,EFNA1B,EFNA3B,EPHA2A,EFNA2,EPHA2,MYL12B,EFNA1,EFNA2A
    EPH-Ephrin signaling EFNA1A,AP2M1,ARPC1B,EFNA4,KALRNB,EFNB2,CLTB,MYL12A,ITSN1,EFNA1
    Endocytosis SH3GLB2,AP2M1B,CDC42L2,CDC42L,PML,CHMP4C,ADRB3A,WAS,SNX6,IST1
    Cytokine-cytokine receptor interaction IFN-a,INHBB,CCL24,CXCL2,IL7R,IL21R,CXCR4B,CCL27,BMP2,CSF1R

    Protein Function

    Kdr has several biochemical functions, for example, ATP binding,growth factor binding,integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Kdr itself. We selected most functions Kdr had, and list some proteins which have the same functions with Kdr. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CDK13,EPHB3A,DYRK1A,MCM2,IRAK4,GALK1,CLK1,MAPK11,NUBP1,DYNC1LI1
    integrin binding ADAM23,PXN,ADAM2,CALR,S1PR2,AMICA1,PPAP2B,ACTN2,ITGB1BP2,CD226
    vascular endothelial growth factor-activated receptor activity NRP1A,NRP1B,FLT4,NRP1,FLT1,FLT3,NRP2B,PDGFRA,NRP2A,NRP2
    vascular endothelial growth factor binding NRP1,PDGFRA,PDGFRB
    growth factor binding A2M,NRP2,BMPR2,REG3B,LTBP2,ERBB3,LTBP4,SDCBP,NRP1,IL6ST
    protein binding POU2AF1,ARL8A,SLC7A11,MAGED1,ANO6,COLQ,RNF220,ENTPD3,HPS4,AHCYL2
    protein tyrosine kinase activity LCK,ZNF143B,MAP2K4,CLK2,EPHB4B,PDGFRB,TNK2B,TNK2,MATK,DYRK1A

    Interacting Protein

    Kdr has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Kdr here. Most of them are supplied by our site. Hope this information will be useful for your research of Kdr.

    Resources

    Research Area

    Cancer Drug Targets
    Endothelial Cell Markers
    VEGF Receptors and Regulators on Endothelial Cells
    Cytokine and Growth Factor Receptors on VSMC
    Hemangioblast Markers
    CD Antigen (Hematopoietic Stem Cell Markers)
    Receptor Tyrosine Kinases (RTKs)
    Endothelial Cell Differentiation Markers
    Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
    Negative Regulators of the Jak/STAT Pathway
    Receptors in the Jak/STAT Pathway
    Hematopoietic Stem Cell Markers
    VEGF Family
    Semaphorins, Plexin Receptors, and Related Molecules
    VEGF Receptor
    Mesodermal Lineage Markers
    MDSC Phenotyping - Positive Markers
    Glioma Biomarkers
    CAR-T Cell Therapy Targets

    References

    • Verbeke, SLJ; de Jong, D; et al. Array CGH Analysis Identifies Two Distinct Subgroups of Primary Angiosarcoma of Bone. GENES CHROMOSOMES & CANCER 54:72-81(2015).
    • Verma, VK; Kamaraju, SR; et al. Fluorescent magnetic iron oxide nanoparticles for cardiac precursor cell selection from stromal vascular fraction and optimization for magnetic resonance imaging. INTERNATIONAL JOURNAL OF NANOMEDICINE 10:711-726(2015).

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