Recombinant Human KDR Protein, DDK-tagged

Cat.No. : KDR-959H
Product Overview : Recombinant Human KDR(Met-Leu834-Lys1162) fused with DDK tag at C-terminal was expressed in Sf9 cells.
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Species : Human
Source : Sf9 Cells
Tag : Flag
Protein Length : -834 a.a.
Description : Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Form : 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
Molecular Mass : 37.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name KDR kinase insert domain receptor (a type III receptor tyrosine kinase) [ Homo sapiens ]
Official Symbol KDR
Synonyms KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor;
Gene ID 3791
mRNA Refseq NM_002253
Protein Refseq NP_002244
MIM 191306
UniProt ID P35968

Not For Human Consumption!

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