FCGRT
-
Official Full Name
Fc fragment of IgG, receptor, transporter, alpha -
Overview
This gene binds and transports maternal immunoglobulin gamma from milk, and plays a role in providing maternal immunity to neonates. -
Synonyms
FCGRT;Fc fragment of IgG, receptor, transporter, alpha;IgG receptor FcRn large subunit p51;alpha chain;FCRN;FcRn alpha chain;neonatal Fc receptor;neonatal Fc-receptor for Ig;IgG Fc fragment receptor transporter alpha chain;immunoglobulin receptor
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Rhesus macaque
- Rat
- Human Cell
- E.coli
- Mammalian cells
- HEK293
- Mammalian Cell
- Wheat Germ
- HEK293T
- Yeast
- E.coli expression system
- His
- His&StrepII&Avi
- Non
- GST
- His&Avi
- Myc&DDK
- Flag
- His&Fc&Avi
- His&T7
- Avi
- His&SUMO
- Flag&Myc
Involved Pathway
FCGRT involved in several pathways and played different roles in them. We selected most pathways FCGRT participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FCGRT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FCGRT has several biochemical functions, for example, IgG binding,IgG receptor activity,beta-2-microglobulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCGRT itself. We selected most functions FCGRT had, and list some proteins which have the same functions with FCGRT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| IgG receptor activity | FCGR1 |
| beta-2-microglobulin binding | CD1E,CD1D2,CD1C,CD1D,CD1B,CD1A,HLA-E,HFE,CD1d1,H2-Q10 |
| NOT peptide antigen binding | HFE |
| IgG binding | CD247L,cgr2b,FCGR2B,FCGR1A,FCGR2C,FCGR2A,FCGR1B,FCGR3A,FCER1G,PIP |
Interacting Protein
FCGRT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCGRT here. Most of them are supplied by our site. Hope this information will be useful for your research of FCGRT.
B2M;q81zd5_bacan;q8d0i9_yerpe;aceB
Resources
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References
- Uno, Y; Utoh, M; et al. Polymorphisms of Neonatal Fc Receptor in Cynomolgus and Rhesus Macaques. DRUG METABOLISM AND PHARMACOKINETICS 29:427-430(2014).
- Cervenak, J; Doleschall, M; et al. NF kappa B induces overexpression of bovine FcRn A novel mechanism that further contributes to the enhanced immune response in genetically modified animals carrying extra copies of FcRn. MABS 5:860-871(2013).
