Recombinant Human FCGRT Protein, His-Avi-tagged

• Cat.No.: FCGRT-937H
• Product Overview: Human FcRn is expressed from mammalian with a His tag and Avi Tag at the C-terminal. It contains Ile 21 - Met 119(B2M)& Ala 24 - Ser 297 (FCGRT).

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Ile 21 - Met 119(B2M)& Ala 24 - Ser 297 (FCGRT)
• Description: The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Endotoxin: Less than 0.5 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE. > 95% as determined by HPLC.
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: FCGRT Fc fragment of IgG receptor and transporter [ Homo sapiens (human) ]
• Official Symbol: FCGRT
• Synonyms: FCRN; alpha-chain
• Gene ID: 2217
• mRNA Refseq: NM_001136019.3
• Protein Refseq: NP_001129491.1
• MIM: 601437
• UniProt ID: P55899