CD47

  • Official Full Name

    CD47 molecule

  • Overview

    alphaVbeta3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed by platelets. Furthermore it is a receptor for phagocytosis on macrophages or dendritic cells. Inhibitors like etaracizumab may be used as antiangiogenics.

  • Synonyms

    CD47;CD47 molecule;CD47 antigen (Rh related antigen, integrin associated signal transducer), MER6;leukocyte surface antigen CD47;antigen identified by monoclonal 1D8;antigenic surface determinant protein OA3;CD47 glycoprotein;IAP;integrin associated protein;OA3;Rh related antigen;Rh-related antigen;integrin-associated protein;integrin-associated signal transducer;CD47 antigen (Rh-related antigen, integrin-associated signal transducer);MER6

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • Cynomolgus/Rhesus macaque
  • Chicken
  • Rabbit
  • Rhesus macaque
  • Cynomolgus
  • Bovine
  • Canine
  • Mus musculus
  • Sus scrofa (Pig)
  • Pongo Abelii
  • HEK293
  • Insect Cell
  • Mammalian cells
  • CHO cells
  • Human Cell
  • Wheat Germ
  • Mammalian Cell
  • E.coli
  • Sf9 Insect Cell
  • Mammalian Cells
  • Human cells
  • Human Cells
  • Protein Conjugation
  • In Vitro Cell Free System
  • E.coli expression system
  • His&Avi
  • His
  • Fc
  • Non
  • His&Fc
  • lIgG2b
  • LEVLFQ
  • rFc
  • Fc&Avi&Biotin
  • Fc&Avi
  • His&Flag&StrepII
  • GST
  • His&Flag
  • Flag
  • His&T7
  • His&Fc&Avi
  • mIgG2a
  • His&mFc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CD47-556H Recombinant Human CD47 protein, His-Avi-tagged, Biotinylated HEK293 Human His&Avi GIn19-Pro139
CD47-7862H Recombinant Human CD47 protein, His-tagged HEK293 Human His Gln19-Pro139
Cd47-647MF Recombinant Mouse Cd47 Protein, His-tagged, FITC conjugated HEK293 Mouse His Met1-Lys140, 133
CD47-3095M Recombinant Mouse Cd47 protein, Fc-tagged HEK293 Mouse Fc Gln19-Pro158
Cd47-7480R Recombinant Rat Cd47 protein, Fc-tagged HEK293 Rat Fc Gln19-Lys140
CD47-7865H Recombinant Human CD47 protein(Met1-Pro139) HEK293 Human Non Met1-Pro139
Cd47-8767R Active Recombinant Rat Cd47, His tagged HEK293 Rat His Met1-Lys140
CD47-14H Active Recombinant Human CD47 Protein, hIgG/His-tagged Insect Cell Human His&Fc 19-141
CD47-3292H Recombinant Human CD47 protein, His-tagged, low endotoxin HEK293 Human His Gln19-Pro139
CD47-347H Active Recombinant Human CD47 Protein, LIgG2b Fc-tagged, low endotoxin HEK293 Human lIgG2b Gln 19 - Pro 139
CD47-380M Recombinant Mouse CD47 protein (Met1-Lys140) HEK293 Mouse 1-140 a.a.
CD47-382M Active Recombinant Mouse CD47 protein, His-tagged HEK293 Mouse His Gln19-Lys140
Cd47-647MAF488 Recombinant Mouse Cd47 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 Mouse His Met1-Lys140, 133
Cd47-647MAF555 Recombinant Mouse Cd47 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 Mouse His Met1-Lys140, 133
Cd47-647MAF647 Recombinant Mouse Cd47 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 Mouse His Met1-Lys140, 133
Cd47-7480RAF488 Recombinant Rat Cd47 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 Rat Fc Gln19-Lys140
Cd47-7480RAF555 Recombinant Rat Cd47 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 Rat Fc Gln19-Lys140
Cd47-7480RAF647 Recombinant Rat Cd47 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 Rat Fc Gln19-Lys140
Cd47-7480RF Recombinant Rat Cd47 Protein, hFc-tagged, FITC conjugated HEK293 Rat Fc Gln19-Lys140
CD47-7865HAF488 Recombinant Human CD47 Protein, Alexa Fluor 488 conjugated HEK293 Human LEVLFQ Met1-Pro139, 128
CD47-7865HAF555 Recombinant Human CD47 Protein, Alexa Fluor 555 conjugated HEK293 Human LEVLFQ Met1-Pro139, 128
CD47-7865HAF647 Recombinant Human CD47 Protein, Alexa Fluor 647 conjugated HEK293 Human LEVLFQ Met1-Pro139, 128
CD47-7865HF Recombinant Human CD47 Protein, FITC conjugated HEK293 Human LEVLFQ Met1-Pro139, 128
CD47-7889HAF488 Recombinant Human CD47 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Human Fc 362
CD47-7889HAF555 Recombinant Human CD47 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Human Fc 362
CD47-7889HAF647 Recombinant Human CD47 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Human Fc 362
CD47-7889HF Recombinant Human CD47 Protein, Fc-tagged, FITC conjugated HEK293 Human Fc 362
Cd47-8767RAF488 Recombinant Rat Cd47 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 Rat His 133
Cd47-8767RAF555 Recombinant Rat Cd47 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 Rat His 133
Cd47-8767RAF647 Recombinant Rat Cd47 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 Rat His 133
Cd47-8767RF Recombinant Rat Cd47 Protein, His-tagged, FITC conjugated HEK293 Rat His 133
CD47-892M Recombinant Mouse CD47 Protein (Met1-Lys140), RlgG Fc-tagged HEK293 Mouse rFc Met1-Lys140
Cd47-645M Active Recombinant Mouse Cd47 protein, Fc-tagged Mammalian cells Mouse Fc Gln19-Pro158
CD47-7890H Active Recombinant Human CD47 protein, Fc/Avi-tagged, Biotinylated HEK293 Human Fc&Avi&Biotin Gln 19 - Pro 139
CD47-7891H Active Recombinant Human CD47 Protein, His-tagged, Biotinylated HEK293 Human His Gln 19 - Pro 139
CD47-051H Active Recombinant Human CD47 protein, Fc/Avi-tagged, CHO cells Human Fc&Avi Gln19-Pro139
CD47-101HG Active GMP Recombinant Human CD47 protein HEK293 Human DNA sequence encoding Human CD47(NCBI Reference Sequence: NP_942088.1) was expressed with His tag at the C-terminal.
CD47-1946C Active Recombinant Cynomolgus / Rhesus macaque CD47 protein, Fc-tagged HEK293 Cynomolgus/Rhesus macaque Fc Gln 19 - Glu 141
CD47-2332H Recombinant Human CD47 protein(Met1-Pro139), hFc-tagged HEK293 Human Fc Met1-Pro139
CD47-5495H Active Recombinant Human CD47 Full Length Transmembrane protein(Nanodisc) HEK293 Human Non Full L.
CD47-679C Active Recombinant Cynomolgus / Rhesus macaque CD47 protein, His-tagged HEK293 Cynomolgus/Rhesus macaque His Gln 19 - Glu 141
CD47-7889H Recombinant Human CD47, Fc tagged Human Cell Human Non 1-139 a.a.
CD47-0825H Recombinant Human CD47 Protein Wheat Germ Human Non
CD47-0826H Recombinant Human CD47 Protein, His-Flag-StrepII-Tagged Human Cell Human His&Flag&StrepII 19-141 a.a.
CD47-0827H Recombinant Human CD47 Protein, GST-Tagged Wheat Germ Human GST
CD47-1207C Recombinant Chicken CD47 Mammalian Cell Chicken His
CD47-1255R Recombinant Rat CD47 Protein Mammalian Cell Rat His
CD47-3094M Recombinant Mouse Cd47 protein, His-tagged HEK293 Mouse His Gln19-Pro158
CD47-333H Recombinant CD47 protein, His/Avi-tagged HEK293 Human His&Avi 121
CD47-40H Recombinant Human CD47 protein, hIgG-His-tagged Insect Cell Human His&Fc
Cd47-5727M Recombinant Mouse Cd47 protein, His-tagged E.coli Mouse His Ala18~Gly219
Cd47-646M Recombinant Mouse Cd47 protein, Fc-tagged HEK293 Mouse Fc 122
Cd47-647M Recombinant Mouse Cd47 protein, His-tagged HEK293 Mouse His Met1-Lys140
Cd47-70R Recombinant Rabbit Cd47 protein, Fc-tagged HEK293 Rabbit Fc Gln19-Glu139
CD47-71H Recombinant Human CD47 protein, His-tagged Insect Cell Human His
CD47-743R Recombinant Rhesus monkey CD47 Protein, His-tagged Mammalian Cell Rhesus macaque His
CD47-745C Recombinant Cynomolgus/Rhesus macaque CD47 protein, Fc-tagged HEK293 Cynomolgus/Rhesus macaque Fc Gln4-Glu126
CD47-834H Recombinant Human CD47 Protein, Fc-tagged HEK293 Human Fc 19-141 a.a.
CD47-835H Recombinant Human CD47 Protein, DDK/His-tagged HEK293 Human His&Flag 19-141 a.a.
CD47-836H Recombinant Human CD47 Protein, DDK-tagged Sf9 Insect Cell Human Flag -19 a.a.
CD47-837H Recombinant Human CD47 Protein, Fc-tagged HEK293 Human Fc
CD47-90H Recombinant Human CD47 protein, T7/His-tagged E.coli Human His&T7 19-127 a.a.
CD47-1363RCL Recombinant Rat CD47 cell lysate Human Cell Rat Non
CD47-850HCL Recombinant Human CD47 cell lysate Human Cell Human Non
CD47 -0245M Recombinant Mouse CD47 protein HEK293 Mouse Non Met1-Lys140
CD47-0248M Recombinant Mouse CD47 protein, Fc -tagged HEK293 Mouse Fc Met1-Lys140
CD47-0252H Recombinant Human CD47 protein, Biotinylated HEK293 Human Non 1-139 a.a.
CD47-0989M Active CD47 protein-coupled magnetic Beads HEK293 Human Gln 19 - Pro 139
CD47-1017C Recombinant Cynomolgus CD47 Protein (Met1-Asn142), HlgG1 Fc-tagged HEK293 Cynomolgus Fc Met1-Asn142
CD47-112B Recombinant Bovine CD47 Protein, His-tagged Mammalian Cells Bovine His Gln19 - Asn140
CD47-113B Recombinant Bovine CD48 Protein, Fc-tagged Mammalian Cells Bovine Fc Gln19 - Asn140
CD47-1239H Recombinant Human CD47 Protein (Gln19-Pro139), N-His tagged E.coli Human His Gln19-Pro139
CD47-1276H Recombinant Human CD47 Protein (Met1-Glu141), C-His tagged Mammalian cells Human His Met1-Glu141
CD47-151H Recombinant Human CD47 Protein, DYKDDDDK-tagged Human cells Human Flag
CD47-152H Recombinant Human CD47 Protein, DYKDDDDK-tagged Human Cells Human Flag
Cd47-18M Recombinant Mouse Cd47 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
Cd47-18M-B Recombinant Mouse Cd47 Protein Pre-coupled Magnetic Beads HEK293 Mouse
CD47-199H Recombinant Human CD47 Protein, C-His-tagged E.coli Human His
CD47-1B Recombinant Bovine CD47 Protein, His (Fc)-Avi-tagged HEK293 Bovine His&Fc&Avi
CD47-1B-B Recombinant Bovine CD47 Protein Pre-coupled Magnetic Beads HEK293 Bovine
CD47-2153H Recombinant Human CD47 Protein, His-tagged E.coli Human His Ala18-Glu141
CD47-2186H Active Recombinant Human CD47 protein, His-tagged HEK293 Human His Met1-Pro139
CD47-2784H Recombinant Human CD47 Protein, His-tagged, OVA Conjugated Protein Conjugation Human His Glu308-Glu323
CD47-2993HF Recombinant Full Length Human CD47 Protein In Vitro Cell Free System Human Full L. 99 amino acids
CD47-2996HF Recombinant Full Length Human CD47 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 323 amino acids
CD47-33H Recombinant Human CD47 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Human His&Fc Gln19-Pro139
CD47-346C Recombinant Cynomolgus/Rhesus macaque CD47 protein, His-tagged HEK293 Cynomolgus/Rhesus macaque His 123
CD47-348H Recombinant Human CD47 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Human mIgG2a 121
CD47-384M Recombinant Mouse CD47 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse mIgG2a 122
CD47-508H Recombinant Human CD47 Protein (Gln19-Gln141, Val198-Ala207, Ser257-Gly268), C-mFc and 6×His-tagged HEK293 Human His&mFc Gln19-Gln141, Val198-Ala207, Ser257-Gly268
CD47-527H Recombinant Human CD47 protein, hFc-tagged HEK293 Human Fc Gln19-Pro139
CD47-555H Recombinant Human CD47 Protein (Met1-Pro139), His-tagged Insect Cell Human His Met1-Pro139
CD47-569R Recombinant Rhesus Macaque CD47 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
CD47-569R-B Recombinant Rhesus Macaque CD47 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Cd47-5707M Recombinant Mouse Cd47 Protein (Met1-Ile162), C-His tagged Mammalian cells Mouse His Met1-Ile162
CD47-638C Recombinant Cynomolgus monkey CD47 Protein, Fc-tagged HEK293 Cynomolgus Fc 307
CD47-639H Recombinant Human CD47 Protein HEK293 Human 323
CD47-640H Recombinant Human CD47 Protein, Fc-tagged HEK293 Human Fc 323
CD47-641H Recombinant Human CD47 Protein, IgG2a Fc-tagged HEK293 Human Fc 323
CD47-642M Recombinant Mouse CD47 Protein, Fc-tagged HEK293 Mouse Fc 303
CD47-643R Recombinant Rabbit CD47 Protein, Fc-tagged HEK293 Rabbit Fc 321
CD47-644R Recombinant Rat CD47 Protein, Fc-tagged HEK293 Rat Fc 303
CD47-645H Recombinant Human CD47 Protein, His and Avi-tagged HEK293 Human His&Avi 323
CD47-674C Recombinant Cynomolgus/Rhesus macaque CD47 protein, His-tagged HEK293 Cynomolgus/Rhesus macaque His Met1-Asn142
CD47-745R Recombinant Rhesus Macaque CD47(Gln19-Glu141) Protein, N-6*His-Flag-tagged HEK293 Rhesus macaque His&Flag 19-141 a.a.
CD47-7865HB Recombinant Human CD47 protein, LEVLFQ-tagged, Biotinylated HEK293 Human LEVLFQ 1-139 a.a.
CD47-862C Recombinant Canine CD47 protein, His-tagged HEK293 Canine His Gln 19 - Asn 140
CD47-913R Recombinant Rat CD47 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
CD47-913R-B Recombinant Rat CD47 Protein Pre-coupled Magnetic Beads HEK293 Rat
CD47-987M PE-labeled CD47 protein-coupled magnetic Beads Human
Kit-1706 CD47:SIRP-α[Biotinylated] Inhibitor Screening Assay Kit Non
RFL14932MF Recombinant Full Length Mouse Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length of Mature Protein (19-303)
RFL17555SF Recombinant Full Length Pig Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system Sus scrofa (Pig) His Full L. Full Length of Mature Protein (19-303)
RFL25841BF Recombinant Full Length Bovine Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system Bovine His Full L. Full Length of Mature Protein (19-303)
RFL27649RF Recombinant Full Length Rat Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system Rat His Full L. Full Length of Mature Protein (19-303)
RFL31430PF Recombinant Full Length Pongo Abelii Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system Pongo Abelii His Full L. Full Length of Mature Protein (19-323)

    Involved Pathway

    CD47 involved in several pathways and played different roles in them. We selected most pathways CD47 participated on our site, such as ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD47 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ECM-receptor interaction COL3A1,ITGA6,SPP1,HMMR,SV2B,ITGA7,COL4A6,THBS2,COL2A1,ITGA3B

    Protein Function

    CD47 has several biochemical functions, for example, protein binding,thrombospondin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD47 itself. We selected most functions CD47 had, and list some proteins which have the same functions with CD47. You can find most of the proteins on our site.

    Function Related Protein
    thrombospondin receptor activity F2,SDC4
    protein binding GTF2H4,HMG20B,PRPF4B,RPS13,GM5506,HIST1H2AG,PLK1,PPP1R37,CTCFL,PAPD4

    Interacting Protein

    CD47 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD47 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD47.

    SYNE4;SIRPG;b3xyc5_sollc

    Resources

    Research Area

    Cancer Drug Targets
    Immune Regulatory Molecules on Endothelial Cells
    Immunoglobulin Superfamily CAMs
    Leukemia Cancer Stem Cell Markers
    Bladder Cancer Stem Cell Markers
    Dendritic Cell Pathogen Recognition/Uptake
    Immune Checkpoints

    References

    • Banerjee, R; Khandelwal, S; et al. CD47 regulates the phagocytic clearance and replication of the Plasmodium yoelii malaria parasite. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:3062-3067(2015).
    • Feng, MY; Chen, JY; et al. Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:2145-2150(2015).

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