Recombinant Human RBBP6 cell lysate

• Cat.No.: RBBP6-1480HCL

Specification

• Species: Human
• Tag: Non
• Description: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: RBBP6 retinoblastoma binding protein 6 [ Homo sapiens ]
• Official Symbol: RBBP6
• Synonyms: RBBP6; retinoblastoma binding protein 6; E3 ubiquitin-protein ligase RBBP6; P2P R; PACT; proliferation potential related protein; SNAMA; protein P2P-R; RB-binding Q-protein 1; retinoblastoma-binding Q protein 1; proliferation potential-related protein; p53-associated cellular protein of testis; retinoblastoma-binding protein 6, isoform 3; MY038; P2P-R; RBQ-1; DKFZp686P0638; DKFZp761B2423
• Gene ID: 5930
• mRNA Refseq: NM_006910
• Protein Refseq: NP_008841
• MIM: 600938
• UniProt ID: Q7Z6E9
• Chromosome Location: 16p12.2
• Function: ligase activity; metal ion binding; nucleic acid binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding