Recombinant Human PCSK5, His-tagged

Cat. No. :	PCSK5-122H
Description :	Theprotein encoded by this gene belongs to the subtilisin-like proproteinconvertase family. The members of this family are proprotein convertases thatprocess latent precursor proteins into their biologically active products.This encoded protein mediates posttranslational endoproteolytic processingfor several integrin alpha subunits. It is thought to process prorenin,pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160.Multiple transcript variants encoding different isoforms have been found forthis gene.
Source :	E.coli.
Species :	Human
Antigen peptideregion :	32-351aa
StorageBuffer :	1 M PBS(58 mM Na2HPO4, 17 mM NaH2PO4, 68 mM NaCl, pH8. ) addedwith 300 mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
OfficialSymbol :	PCSK5

Gene Name	PCSK5 proproteinconvertase subtilisin/kexin type 5 [Homo sapiens]
Synonyms	PCSK5; proproteinconvertase subtilisin/kexin type 5; PC5; PC6; PC6A; SPC6; FLJ11149; FLJ16215;hPC6; protease PC6; prohormone convertase 5; proprotein convertase 6; subtilisin/kexin-likeprotease PC5; OTTHUMP00000021497; OTTHUMP00000021498; OTTHUMP00000021499; EC3.4.21.; Proprotein convertase 5; EC 3.4.21; EC 3.4.21.61; EC 3.4.21.75
Gene ID	5125
mRNA Refseq	NM_001190482
Protein Refseq	NP_001177411
MIM	600488
UniProt ID	Q92824
Chromosome Location	9
Pathway	NGFprocessing; Signal Transduction; Signalling by NGF
Function	peptidaseactivity; peptide binding; serine-type endopeptidase activity