Recombinant Human PCSK5, GST-tagged

• Cat.No.: PCSK5-121H
• Product Overview: Recombinant Human PCSK5was produced in vitro wheat germ expression system with GST-tag at N-terminal,128 kDa (913aa).

Specification

• Cat. No.: PCSK5-121H
• Description: Theprotein encoded by this gene belongs to the subtilisin-like proproteinconvertase family. The members of this family are proprotein convertases thatprocess latent precursor proteins into their biologically active products.This encoded protein mediates posttranslational endoproteolytic processingfor several integrin alpha subunits. It is thought to process prorenin,pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160.Multiple transcript variants encoding different isoforms have been found forthis gene.
• amino acid sequence: MGWGSRCCCPGRLDLLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGT HSFISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERT HPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSFNPQ HVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEE CSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSH LYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPS GTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRY SRVEDPTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAPNCESCFGSHGD QCMSCKYGYFLNEETNSCVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNGQDCQPCHR FCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLDLGMCQMGAICKD ATEESWAEGGFCMLVKKNNLCQRKVLQQLCCKTCTFQG
• Source: wheatgerm
• Species: Human
• Purification: GlutathioneSepharose 4 Fast Flow
• Applications: ELISA;WB; Antibody Production; Protein Array
• Note: Bestuse within three months from the date of receipt of this protein.
• StorageBuffer: 50 mMTris-HCI, 10 mM reduced Glutathione, pH8.0 in the elution buffer.
• Storage: Storeat -80°C. Aliquot to avoid repeated freezing and thawing.
• OfficialSymbol: PCSK5

Gene Information

• Gene Name: PCSK5 proproteinconvertase subtilisin/kexin type 5 [Homo sapiens]
• Synonyms: PCSK5; proproteinconvertase subtilisin/kexin type 5; PC5; PC6; PC6A; SPC6; FLJ11149; FLJ16215;hPC6; protease PC6; prohormone convertase 5; proprotein convertase 6; subtilisin/kexin-likeprotease PC5; OTTHUMP00000021497; OTTHUMP00000021498; OTTHUMP00000021499; EC3.4.21.; Proprotein convertase 5; EC 3.4.21; EC 3.4.21.61; EC 3.4.21.75
• Gene ID: 5125
• mRNA Refseq: NM_006200
• Protein Refseq: NP_006191
• MIM: 600488
• UniProt ID: Q92824
• Chromosome Location: 9
• Pathway: NGFprocessing; Signal Transduction; Signalling by NGF
• Function: peptidaseactivity; peptide binding; serine-type endopeptidase activity