Recombinant Human Interleukin 5

• Cat.No.: IL5-1240H
• Product Overview: Recombinant human IL5,produced in e. coli, is a non-glycosylated homodimer with each polypeptidechain containing 132 amino acids with a total MW 26.52284 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: The protein encoded by thisgene is a cytokine that acts as a growth and differentiation factor for bothB cells and eosinophils. This cytokine is a main regulator of eosinopoiesis,eosinophil maturation and activation. The elevated production of thiscytokine is reported to be related to asthma or hypereosinophilic syndromes.
• Form: The protein waslyophilized from a concentrated (10mg/ml) solution with no additives.
• Storage: Lyophilizedrecombinant human IL-5, although stable at room temperature, should be storeddesiccated below 0°C. Reconstituted recombinant human IL-5 is best storedrefrigerated at 4°C.
• OfficialSymbol: IL5

Gene Information

• Gene Name: IL5 interleukin 5(colony-stimulating factor, eosinophil) [ Homo sapiens ]
• Synonyms: IL5; interleukin 5(colony-stimulating factor, eosinophil); EDF; TRF; IL-5; interleukin-5;T-cell replacing factor; B cell differentiation factor I; eosinophildifferentiation factor; OTTHUMP00000065830; B-cell differentiation factor I
• Gene ID: 3567
• mRNA Refseq: NM_000879
• Protein Refseq: NP_000870
• MIM: 147850
• UniProt ID: P05113
• Chromosome Location: 5q31.1
• Pathway: Allograft rejection; Asthma;Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fcepsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signalingpathway; cell receptor signaling pathway
• Function: cytokine activity; growthfactor activity; interleukin-4 receptor binding