Native E.coli Uracil DNA Glycosilase

• Cat.No.: ung-8332E
• Product Overview: E.coli Uracil DNA Glycosilase (UNG) catalyses the release of free Uracil from Uracil-containing DNA. UNG efficiently hydrolyzes uracil from signle-stranded or double-stranded DNA, but not from oligomers (6 fewer bases).

Specification

• Description: UDG and Ndk form a complex (Goswami, 2006). Uracil can be generated in DNA as a result of misincorporation by DNA polymerase, spontaneous deamination of cytosine, and deamination of cytosine induced by bisulfite or nitrous acid.
• Source: E.coli
• Species: E.coli
• Form: 10mM Tris-Hcl (pH-7.4 at 25C), 50mM KCl, 1mM DTT, 0.1mM EDTA, 0.1 mg/ml BSA and 50% glycerol.
• Notes: For research use only.
• Storage: Uracil DNA Glycosilase although stable at 15°C for week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.
• Tag: Non

Gene Information

• Gene Name: ung uracil-DNA-glycosylase [ Escherichia coli str. K-12 substr. MG1655 ]
• Official Symbol: ung
• Synonyms: ECK2578; JW2564
• Gene ID: 947067
• Protein Refseq: NP_417075
• Pathway: Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem

Reviews

09/22/2022

The technician guided me through the process, which led to satisfactory results.

07/14/2022

The UNG protein product received was as advertised, top quality and good value for money.

05/04/2022

Prompt delivery helped me get satisfactory experimental results in a short period of time.

Q&As

What biological processes are UNG involved in?

UNG is involved in DNA repair, base excision repair and apoptosis.

Where is UNG located?

UNG is localized in the nucleus, nucleoplasm, and mitochondria.

What protein does UNG shear to produce?

UNG can be sheared to produce UNG1 and UNG2.

Where is UNG primarily expressed?

UNG is mainly expressed in testis, thymus and skeletal muscle.