Active Native Human Myeloperoxidase

• Cat.No.: MPO -27H
• Product Overview: Myeloperoxidase purified from leucocytes of purulent human sputum which is >98 percent pure.

Specification

• Species: Human
• Source: Human Sputum
• Tag: Non
• Description: Myeloperoxidase is a lysosomal protein stored in azurophilic granules of the neutrophil which produces hypochlorous acid from hydrogen peroxide and chloride anion during the neutrophil respiratory burst.
• Form: Lyophilized powder
• Bio-activity: 155 Units/mg
• Molecular Mass: 59,000 Reduced
• Unit Definition: 1 unit will decompose 1 umole of H2O2 per minute at pH 7.0 and 25 C using 4-amino-antipyrine as hydrogen donor. Recommended assay buffer: 0.1 M KPO4; pH 7.0
• Usage: For in vitro laboratory use only
• Notes: Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet.
• Stability: Supplied as a lyophilized, salt-free, green soluble powder which is stable for over a year when stored at 5 °C.
• Storage: 4°C
• Shipping: Cold pack

Gene Information

• Gene Name: MPO myeloperoxidase [ Homo sapiens ]
• Official Symbol: MPO
• Synonyms: MPO; myeloperoxidase
• Gene ID: 4353
• mRNA Refseq: NM_000250
• Protein Refseq: NP_000241
• MIM: 606989
• UniProt ID: P05164
• Chromosome Location: 17q21.3-q23
• Pathway: C-MYB transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; IL23-mediated signaling events, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; Selenium Pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem
• Function: chromatin binding; heme binding; heparin binding; metal ion binding; oxidoreductase activity; peroxidase activity