Native Human Neutrophil Myeloperoxidase

• Cat.No.: MPO-8220H
• Product Overview: Human Neutrophil Myeloperoxidase was purified from Human Neutrophil.

Specification

• Species: Human
• Source: Human Neutrophil
• Tag: Non
• Description: MPO is a peroxidase enzyme occurs the most in neutrophil granulocytes (a subtype of white blood cells). It is a lysosomal protein stored in azurophilic granules of the neutrophil. Myeloperoxidase has a green heme pigment and is found in pus and some forms of mucus. Myeloperoxidase (MPO) is recognized as an important factor in many inflammatory diseases such as cardiovascular and neurological diseases. MPO-specific imaging agents would thus be highly useful to diagnose early disease, monitor disease progression, and quantify treatment effects.
• Form: 50mM Sodium Acetate, pH 6.0, 0.1M NaCl
• Purity: >98% by SDS-PAGE
• Stability: 2 years
• Storage: 2-8 °C
• Concentration: Typically >1.0 mg protein/ml

Gene Information

• Gene Name: MPO myeloperoxidase [ Homo sapiens ]
• Official Symbol: MPO
• Synonyms: MPO; myeloperoxidase
• Gene ID: 4353
• mRNA Refseq: NM_000250
• Protein Refseq: NP_000241
• MIM: 606989
• UniProt ID: P05164
• Chromosome Location: 17q21.3-q23
• Pathway: C-MYB transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; IL23-mediated signaling events, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; Selenium Pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem
• Function: chromatin binding; heme binding; heparin binding; metal ion binding; oxidoreductase activity; peroxidase activity