Active Native Human MPO Protein

• Cat.No.: MPO-01H
• Product Overview: Native Human MPO Protein was a clear, green solution which was purified from human neutrophils.
  RZ Value: > 0.8 (A430/A280)
  A430, E0.1%=1.19

Specification

• Species: Human
• Source: Neutrophils
• Description: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.
• Form: Powder, lyophilized
• Bio-activity: Activity: Reported in U/vial or U/mg solid
  Specific: Activity Report in U/mg protein
• Purity: > 96 % by SDS-PAGE
• Unit Definition: One unit of Myeloperoxidase will catalyze the consumption of one micromole of hydrogen peroxide and the production of ¼ micromole of tetraguaiacol per minute at pH 7.0 and 25 centigrade.
• Applications: Immunoassay/Immunology, Cardiac, Inflammation
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL 0.05 M phosphate, pH 7.0.
• Storage Buffer: Sodium acetate, pH 6.0.

Gene Information

• Gene Name: MPO myeloperoxidase [ Homo sapiens (human) ]
• Official Symbol: MPO
• Synonyms: MPO; myeloperoxidase; myeloperoxidase; EC 1.11.2.2
• Gene ID: 4353
• mRNA Refseq: NM_000250
• Protein Refseq: NP_000241
• MIM: 606989
• UniProt ID: P05164