TNFRSF4

  • Official Full Name

    tumor necrosis factor receptor superfamily, member 4

  • Overview

    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes

  • Synonyms

    TNFRSF4;tumor necrosis factor receptor superfamily, member 4;tumor necrosis factor receptor superfamily member 4;OX40 antigen;OX40L receptor;tax-transcriptionally activated glycoprotein 1;Ox40;ACT35;CD134;Ly-70;Txgp1;TXGP1L

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • Monkey
  • Cynomolgus/Rhesus macaque
  • Rhesus macaque
  • Rabbit
  • Mus musculus
  • Marmoset
  • HEK293
  • CHO
  • Human Cells
  • NS0
  • Mammalian Cells
  • E.coli
  • Insect Cells
  • Avi&His
  • His
  • Fc
  • Fc&His
  • Avi&Fc
  • Non
  • LEVLFQ
  • rFc
  • hIgG4
  • Flag&His
  • Flag
  • DDK&Myc
  • Avi&Fc&His
  • mFc
  • His&SUMO
  • Fc&Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
TNFRSF4-1826H Recombinant Human TNFRSF4 protein, His-Avi-tagged, Biotinylated HEK293 Human Avi&His Leu29-Ala216
TNFRSF4-3247H Active Recombinant Human TNFRSF4 protein, His-tagged HEK293 Human His Leu 29 - Ala 216
TNFRSF4-520H Active Recombinant Human TNFRSF4, MIgG2a Fc-tagged CHO Human Fc 29-216 a.a.
TNFRSF4-3246H Recombinant Human TNFRSF4, Fc-His tagged Human Cells Human Fc&His 1-216 a.a.
Tnfrsf4-349R Recombinant Rat Tnfrsf4 protein, Fc-tagged HEK293 Rat Fc 191
Tnfrsf4-4200M Active Recombinant Mouse Tnfrsf4 protein, His-tagged HEK293 Mouse His Val 20 - Pro 211
Tnfrsf4-7400M Recombinant Mouse Tnfrsf4 protein, Fc-tagged HEK293 Mouse Fc Val20-Pro211
TNFRSF4-3246HAF488 Recombinant Human TNFRSF4 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Human Fc&His 436
TNFRSF4-3246HAF555 Recombinant Human TNFRSF4 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Human Fc&His 436
TNFRSF4-3246HAF647 Recombinant Human TNFRSF4 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Human Fc&His 436
TNFRSF4-3246HF Recombinant Human TNFRSF4 Protein, Fc/His-tagged, FITC conjugated HEK293 Human Fc&His 436
TNFRSF4-3247HAF488 Recombinant Human TNFRSF4 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 Human His Leu29-Ala216
TNFRSF4-3247HAF555 Recombinant Human TNFRSF4 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 Human His Leu29-Ala216
TNFRSF4-3247HAF647 Recombinant Human TNFRSF4 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 Human His Leu29-Ala216
TNFRSF4-3247HF Recombinant Human TNFRSF4 Protein, His-tagged, FITC conjugated HEK293 Human His Leu29-Ala216
TNFRSF4-339H Recombinant Human TNFRSF4 protein, Fc-tagged HEK293 Human Fc 188
TNFRSF4-341M Active Recombinant Mouse TNFRSF4 Protein, His & Avi-tagged, Biotinylated HEK293 Mouse Avi&His Val 20 - Pro 211
TNFRSF4-442H Active Recombinant Human TNFRSF4 protein, Fc-Avi-tagged, Biotinylated HEK293 Human Avi&Fc Leu 29 - Ala 216
Tnfrsf4-547M Recombinant Mouse Tnfrsf4 Protein HEK293 Mouse Non Met1-Pro211
Tnfrsf4-547MAF488 Recombinant Mouse Tnfrsf4 Protein, Alexa Fluor 488 conjugated HEK293 Mouse LEVLFQ Met1-Pro211， 199
Tnfrsf4-547MAF555 Recombinant Mouse Tnfrsf4 Protein, Alexa Fluor 555 conjugated HEK293 Mouse LEVLFQ Met1-Pro211， 199
Tnfrsf4-547MAF647 Recombinant Mouse Tnfrsf4 Protein, Alexa Fluor 647 conjugated HEK293 Mouse LEVLFQ Met1-Pro211， 199
Tnfrsf4-547MF Recombinant Mouse Tnfrsf4 Protein, FITC conjugated HEK293 Mouse LEVLFQ Met1-Pro211， 199
TNFRSF4-548RAF488 Recombinant Monkey TNFRSF4 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 Monkey His Met1-Ala216， 199
TNFRSF4-548RAF555 Recombinant Monkey TNFRSF4 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 Monkey His Met1-Ala216， 199
TNFRSF4-548RAF647 Recombinant Monkey TNFRSF4 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 Monkey His Met1-Ala216， 199
TNFRSF4-548RF Recombinant Monkey TNFRSF4 Protein, His-tagged, FITC conjugated HEK293 Monkey His Met1-Ala216， 199
TNFRSF4-549RAF488 Recombinant Monkey TNFRSF4 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Monkey Fc Met1-Ala216， 426
TNFRSF4-549RAF555 Recombinant Monkey TNFRSF4 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Monkey Fc Met1-Ala216， 426
TNFRSF4-549RAF647 Recombinant Monkey TNFRSF4 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Monkey Fc Met1-Ala216， 426
TNFRSF4-549RF Recombinant Monkey TNFRSF4 Protein, Fc-tagged, FITC conjugated HEK293 Monkey Fc Met1-Ala216， 426
Tnfrsf4-7400MAF488 Recombinant Mouse Tnfrsf4 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 Mouse Fc Val20-Pro211
Tnfrsf4-7400MAF555 Recombinant Mouse Tnfrsf4 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 Mouse Fc Val20-Pro211
Tnfrsf4-7400MAF647 Recombinant Mouse Tnfrsf4 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 Mouse Fc Val20-Pro211
Tnfrsf4-7400MF Recombinant Mouse Tnfrsf4 Protein, hFc-tagged, FITC conjugated HEK293 Mouse Fc Val20-Pro211
TNFRSF4-843M Recombinant Mouse TNFRSF4 Protein (Met1-Pro211), RlgG Fc-tagged HEK293 Mouse rFc Met1-Pro211
TNFRSF4-103M Active Recombinant Cynomolgus/Rhesus macaque TNFRSF4 protein, His-tagged HEK293 Cynomolgus/Rhesus macaque His Lys 28 - Ala 214
TNFRSF4-441H Active Recombinant Human TNFRSF4, Fc-tagged HEK293 Human Fc 29-214 a.a.
TNFRSF4-521H Active Recombinant Human TNFRSF4, HIgG1 Fc-tagged CHO Human Fc 29-216 a.a.
TNFRSF4-522H Active Recombinant Human TNFRSF4 Protein, Fc-tagged CHO Human Fc 29-214 a.a.
TNFRSF4-523H Active Recombinant Human TNFRSF4 Protein, His-tagged CHO Human His 29-214 a.a.
TNFRSF4-659H Active Recombinant Human TNFRSF4, Fc-tagged, Biotinylated Human Cells Human Fc 29-214 a.a.
TNFRSF4-0591C Active Recombinant Cynomolgus / Rhesus macaque TNFRSF4 protein, His-Avi-tagged, Biotinylated HEK293 Cynomolgus/Rhesus macaque Avi&His 28-214 a.a.
TNFRSF4-19H Active Recombinant Human TNFRSF4 Protein, Fc-tagged, Alexa Fluor® 488 conjugated NS0 Human Fc 29-216 a.a.
TNFRSF4-20H Active Recombinant Human TNFRSF4 Protein, Fc-tagged, Alexa Fluor® 647 conjugated NS0 Human Fc 29-216 a.a.
TNFRSF4-102M Recombinant Rhesus macaque TNFRSF4 protein, Fc-tagged HEK293 Rhesus macaque Fc 187
TNFRSF4-115R Recombinant Rabbit TNFRSF4 protein, Fc-tagged HEK293 Rabbit Fc 190
TNFRSF4-1565R Recombinant Rhesus Monkey TNFRSF4 Protein HEK293 Rhesus macaque Non 29-214 a.a.
TNFRSF4-1566R Recombinant Rhesus Monkey TNFRSF4 Protein, hIgG4-tagged HEK293 Rhesus macaque hIgG4 29-214 a.a.
TNFRSF4-27215TH Recombinant Human TNFRSF4, Fc-tagged Human Fc 26-207 a.a.
TNFRSF4-455H Recombinant Human TNFRSF4, Fc Chimera HEK293 Human Fc 93-330 a.a.
TNFRSF4-6200R Recombinant Rat TNFRSF4 Protein Mammalian Cells Rat His
TNFRSF4-670H Recombinant Human TNFRSF4 protein, Fc-tagged HEK293 Human Fc Leu 29 - Ala 216
Tnfrsf4-7075M Recombinant Mouse Tnfrsf4 protein, His-tagged E.coli Mouse His Lys29~Gly210
TNFRSF4-871H Recombinant Human TNFRSF4 Protein, DDK/His-tagged HEK293 Human Flag&His 29-214 a.a.
TNFRSF4-967H Recombinant Human TNFRSF4 Insect Cells Human Non Full L.
TNFRSF4-1762MCL Recombinant Mouse TNFRSF4 cell lysate Human Cells Mouse Non
TNFRSF4-2422HCL Recombinant Human TNFRSF4 cell lysate Human Cells Human Non
RFL10978MF Recombinant Full Length Mouse Tumor Necrosis Factor Receptor Superfamily Member 4(Tnfrsf4) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length of Mature Protein (20-272)
RFL13373RF Recombinant Full Length Rat Tumor Necrosis Factor Receptor Superfamily Member 4(Tnfrsf4) Protein, His-Tagged E.coli Rat His Full L. Full Length of Mature Protein (20-271)
RFL34482HF Recombinant Full Length Human Tumor Necrosis Factor Receptor Superfamily Member 4(Tnfrsf4) Protein, His-Tagged E.coli Human His Full L. Full Length of Mature Protein (29-277)
TNFRSF4-0592M Active Recombinant Mouse TNFRSF4 protein, Fc-tagged HEK293 Mouse Fc 20-211 a.a.
TNFRSF4-0593R Recombinant Rat TNFRSF4 protein, Fc-tagged HEK293 Rat Fc 20-210 a.a.
TNFRSF4-0594R Recombinant Rabbit TNFRSF4 protein, Fc-tagged HEK293 Rabbit Fc 19-208 a.a.
TNFRSF4-0595H Recombinant Human TNFRSF4 protein, hFc-tagged HEK293 Human Fc Leu29-Ala216
TNFRSF4-05H Active Recombinant Human TNFRSF4 Protein, hIgG/His-tagged Insect Cells Human Fc&His 29-214 a.a.
TNFRSF4-1153H Recombinant Human TNFRSF4 Protein (Met1-Ala216), HlgG1 Fc-tagged HEK293 Human Fc Met1-Ala216
TNFRSF4-115HG Active GMP Recombinant Human TNFRSF4 protein HEK293 Human DNA sequence encoding Human OX40(NCBI Reference Sequence: NP_003318.1) was expressed with His tag at the C-terminal.
TNFRSF4-152H Recombinant Human TNFRSF4 Protein, DYKDDDDK-tagged Human Cells Human Flag
TNFRSF4-1907R Recombinant Rabbit TNFRSF4 protein, His-tagged HEK293 Rabbit His Ala 19 - Gln 208
TNFRSF4-1922R Active Recombinant Rat TNFRSF4 protein, His-tagged HEK293 Rat His Val 20 - Pro 210
TNFRSF4-192M TNFRSF4 protein-coupled magnetic MicroBeads Rat
TNFRSF4-2034H Recombinant Human TNFRSF4 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
TNFRSF4-2221H Recombinant Human TNFRSF4 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
TNFRSF4-2221H-B Recombinant Human TNFRSF4 Protein Pre-coupled Magnetic Beads HEK293 Human
TNFRSF4-236H Recombinant Human tumor necrosis factor receptor superfamily, member 4 Protein, His tagged HEK293 Human His 29-214aa
TNFRSF4-239H Recombinant Human TNFRSF4 Protein, hIgG-His-tagged Insect Cells Human Fc&His 29-214aa
TNFRSF4-2764H Recombinant Human TNFRSF4 protein(141-210 aa), C-His-tagged E.coli Human His 141-210 aa
TNFRSF4-338H Active Recombinant Human TNFRSF4 protein, mFc-tagged HEK293 Human mFc Leu 29 - Ala 216
TNFRSF4-340M Active Recombinant Marmoset TNFRSF4 protein, His-tagged HEK293 Marmoset His Leu 29 - Ala 214
TNFRSF4-345H Recombinant Human TNFRSF4 protein, His-Avi-tagged HEK293 Human Avi&His Leu29-Ala216
TNFRSF4-3564H Recombinant Human TNFRSF4 protein, hFc-tagged, Biotinylated(Primary Amine Labeling) HEK293 Human Fc Leu29-Ala216
Tnfrsf4-3602M Recombinant Mouse Tnfrsf4 protein, His-SUMO-tagged E.coli Mouse His&SUMO 20-211aa
TNFRSF4-393H Active Recombinant Human TNFRSF4 Protein (Met1-Ala216), His-tagged, Biotinylated HEK293 Human His Met1-Ala216
Tnfrsf4-450R Recombinant Rat Tnfrsf4 Protein, His-tagged E.coli Rat His Lys29-Gly210
TNFRSF4-4989H Recombinant Human TNFRSF4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
TNFRSF4-5154H Recombinant Human TNFRSF4 Protein (Met1-Ala216), C-His tagged Mammalian Cells Human His Met1-Ala216
TNFRSF4-5155H Recombinant Human TNFRSF4 Protein (Leu29-Ala216), C-Fc tagged Mammalian Cells Human Fc Leu29-Ala216
TNFRSF4-548R Recombinant Rhesus TNFRSF4 Protein, His-tagged HEK293 Rhesus macaque His Met1-Ala216
TNFRSF4-549R Recombinant Rhesus TNFRSF4 Protein, Fc-tagged HEK293 Rhesus macaque Fc Met1-Ala216
Tnfrsf4-5752M Recombinant Mouse Tnfrsf4 Protein (Val20-Pro211), C-Fc tagged Mammalian Cells Mouse Fc Val20-Pro211
TNFRSF4-5857R Recombinant Rat TNFRSF4 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
TNFRSF4-5857R-B Recombinant Rat TNFRSF4 Protein Pre-coupled Magnetic Beads HEK293 Rat
Tnfrsf4-6548M Recombinant Mouse Tnfrsf4 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
Tnfrsf4-6763M Recombinant Mouse Tnfrsf4 Protein (Val20-Pro211), C-His tagged Mammalian Cells Mouse His Val20-Pro211
Tnfrsf4-6764M Recombinant Mouse Tnfrsf4 Protein (Val20-Pro211), N-Fc tagged Mammalian Cells Mouse Fc Val20-Pro211
TNFRSF4-680H Recombinant Human TNFRSF4 Protein HEK293 Human 277
TNFRSF4-681H Recombinant Human TNFRSF4 Protein (Leu29-Ala216), C-hFc and 6×His-tagged HEK293 Human Fc&His Leu29-Ala216
TNFRSF4-682M Recombinant Mouse TNFRSF4 Protein HEK293 Mouse 272
TNFRSF4-683M Recombinant Mouse TNFRSF4 Protein, Fc-tagged HEK293 Mouse Fc 272
TNFRSF4-684R Recombinant Rabbit TNFRSF4 Protein, Fc-tagged HEK293 Rabbit Fc 267
TNFRSF4-685R Recombinant Rat TNFRSF4 Protein, Fc-tagged HEK293 Rat Fc 271
TNFRSF4-686M Recombinant Mouse TNFRSF4 Protein HEK293 Mouse 272
TNFRSF4-687M Recombinant Mouse TNFRSF4 Protein, Fc-tagged HEK293 Mouse Fc 272
TNFRSF4-7475H Recombinant Human TNFRSF4 protein, hFc-Myc-tagged HEK293 Human Fc&Myc 29-216aa
TNFRSF4-982HFL Recombinant Full Length Human TNFRSF4 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.

    Involved Pathway

    TNFRSF4 involved in several pathways and played different roles in them. We selected most pathways TNFRSF4 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNFRSF4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CRLF2,TNFRSF8,RELT,IL23R,TNFSF9,CCL25,IL12B,EDAR,IFNL3,CCL28

    Protein Function

    TNFRSF4 has several biochemical functions, for example, tumor necrosis factor-activated receptor activity,virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TNFRSF4 itself. We selected most functions TNFRSF4 had, and list some proteins which have the same functions with TNFRSF4. You can find most of the proteins on our site.

    Function Related Protein
    virus receptor activity NCAM1,ANPEP,F11R,SLC20A2,HAVCR1,HYAL2,EFNB2,CD4,CD80,SERPINB3
    tumor necrosis factor-activated receptor activity NRADD,TNFRSF8,EDA2R,Tnfrsf26,TNFRSF1B,TNFRSF14,TNFRSF18,TNFRSF10D,LTBR,TNFRSF6B

    Interacting Protein

    TNFRSF4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNFRSF4 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNFRSF4.

    TNFRSF4 Related Signal Pathway

    Resources

    Research Area

    Cancer Drug Targets
    B Cell CD Antigen
    Co-stimulatory TNF Superfamily Molecules
    T Cell Markers
    CD Antigen (Regulatory T Cells)
    TNF Receptor
    Autoimmune Disease Therapeutic Targets
    Co-stimulatory Molecules
    T Follicular Helper (Tfh) Cells
    Immune Checkpoints

    References

    • Aranda, F; Vacchelli, E; et al. Immunostimulatory monoclonal antibodies in cancer therapy. ONCOIMMUNOLOGY 3:-(2014).
    • Lambracht-Washington, D; Rosenberg, RN; et al. Co-stimulation with TNF receptor superfamily 4/25 antibodies enhances in-vivo expansion of CD4+CD25+Foxp3+T cells (Tregs) in a mouse study for active DNA A beta 42 immunotherapy. JOURNAL OF NEUROIMMUNOLOGY 278:90-99(2015).

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