ST3GAL3
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Official Full Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -
Overview
plays a role in the formation of terminal carbohydrate groups of glycolipids and glycoproteins -
Synonyms
ST3GAL3;ST3 beta-galactoside alpha-2,3-sialyltransferase 3;CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase;ST3 beta galactoside alpha 2,3 sialyltransferase 3;4GlcNAc alpha 2 3 sialyltransferase;Alpha 2 3 sialyltransferase II;Alpha 2 3 sialyltransferase III;Alpha 2 3 ST 3;Beta galactoside alpha3 sialyltransferase 3;CMP N acetylneuraminate beta 1 4 galactoside alpha 2 3 sialyltransferase;EC 2.4.99.6;Gal beta 1 3;Gal beta 1 3(4) GlcNAc alpha 2 3 sialyltransferase;Gal beta 1 3(4)GlcNAc alpha 2 3 sialyltransferase;N acetyllactosaminide alpha 2 3 sialyltransferase;OTTHUMP00000008820;OTTHUMP00000008821;OTTHUMP00000008822;OTTHUMP00000008823;Sialyltransferase 6;Sialyltransferase 6 (N acetyllacosaminide alpha 2 3 sialyltransferase);SIAT6;ST3 beta galactoside alpha 2 3 sialyltransferase 3;ST3Gal III;ST3GALII;ST3GalIII;ST3N;alpha 2,3-ST 3;beta-galactoside alpha-2,3-sialyltransferase 3;N-acetyllacosaminide alpha 2,3-sialyltransferase;N-acetyllactosaminide alpha-2,3-sialyltransferase;gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase;sialyltransferase (N-acetyllacosaminide alpha 23-sialyltransferase);sialyltransferase 6(N-acetyllacosaminide alpha 23-sialyltransferase);sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase)
Recombinant Proteins
- Mouse
- Human
- Chicken
- Rat
- Mus musculus
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- E.coli expression system
- In Vitro Cell Free System
- His
- GST
- Non
- His&SUMO
- His&GFP
- His&Fc&Avi
Involved Pathway
ST3GAL3 involved in several pathways and played different roles in them. We selected most pathways ST3GAL3 participated on our site, such as Other types of O-glycan biosynthesis,Glycosaminoglycan biosynthesis - keratan sulfate,Glycosphingolipid biosynthesis - lacto and neolacto series, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST3GAL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Other types of O-glycan biosynthesis | LFNG,POFUT1,POMT2,ST6GAL2,C3orf64,MGAT5B,B3GAT1,B3GALTLB,POMGNT1,GXYLT1 |
| Glycosphingolipid biosynthesis - lacto and neolacto series | ST3GAL6,GGTA1,FUT4,FUT7,B3GNT5B,B3GALT2,B3GALT5,FUT5,GCNT2,B3GNT5A |
| Metabolic pathways | NTPCR,GNS,FECH,MOGAT3,PCK2,NDUFA12,ALDH18A1,NDUFA5,SC4MOL,TYRP1 |
| Glycosaminoglycan biosynthesis - keratan sulfate | CHST2,ST3GAL3B,B4GALT2,FUT8,B4GALT4,CHST4,ST3GAL1,CHST2A,Chst5,B3GNT1 |
Protein Function
ST3GAL3 has several biochemical functions, for example, N-acetyllactosaminide alpha-2,3-sialyltransferase activity,beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST3GAL3 itself. We selected most functions ST3GAL3 had, and list some proteins which have the same functions with ST3GAL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-galactoside (CMP) alpha-2,3-sialyltransferase activity | ST3GAL5,ST3GAL2,ST3GAL1,ST3GAL5L,ST3GAL3B,ST3GAL3A,ST3GAL2L,ST3GAL4 |
| N-acetyllactosaminide alpha-2,3-sialyltransferase activity | ST3GAL3A,ST3GAL3B |
Interacting Protein
ST3GAL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST3GAL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST3GAL3.
ZBTB5;SCAMP2;TTR;RPL8;ACTG1
Resources
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References
- Radhakrishnan, P; Chachadi, V; et al. TNF alpha enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 409:436-441(2011).
- Hatzfeld, A; Eid, P; et al. A sub-population of high proliferative potential-quiescent human mesenchymal stem cells is under the reversible control of interferon alpha/beta. LEUKEMIA 21:714-724(2007).
