Recombinant Full Length Human ST3GAL3 Protein, GST-tagged

• Cat.No.: ST3GAL3-502HF
• Product Overview: Recombinant full length Human ST3GAL3 (1 a.a. - 390 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Description: The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with autosomal recessive nonsymdromic mental retardation-12 (MRT12). Multiple transcript variants encoding several different isoforms have been found for this gene.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 70.2 kDa
• Protein length: 390 amino acids
• AA Sequence: MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSS KYSHSSSPQE KPVADSVVLS FDSAGQTLGS EYDRLGFLLN LDSKLPAELA TKYANFSEGA CKPGYASALM TAIFPRFSKP APMFLDDSFR KWARIREFVP PFGIKGQDNL IKAILSVTKE YRLTPALDSL RCRRCIIVGN GGVLANKSLG SRIDDYDIVV RLNSAPVKGF EKDVGSKTTL RITYPEGAMQ RPEQYERDSL FVLAGFKWQD FKWLKYIVYK ERVSASDGFW KSVATRVPKE PPEIRILNPY FIQEAAFTLI GLPFNNGLMG RGNIPTLGSV AVTMALHGCD EVAVAGFGYD MSTPNAPLHY YETVRMAAIK ESWTHNIQRE KEFLRKLVKA RVITDLSSGI
• Applications: ELISA; WB-Re; AP; Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 [ Homo sapiens (human) ]
• Official Symbol: ST3GAL3
• Synonyms: ST3GAL3; ST3N; MRT12; SIAT6; EIEE15; ST3GALII; ST3GalIII; ST3 beta-galactoside alpha-2,3-sialyltransferase 3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; ST3Gal III; alpha 2,3-ST 3; alpha-2,3-sialyltransferase II; alpha 2,3-sialyltransferase III; Gal beta-1,3(4)GlcNAc alpha-2,3 sialyltransferase; sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase)
• Gene ID: 6487
• mRNA Refseq: NM_174964
• Protein Refseq: NP_777624
• MIM: 606494
• UniProt ID: Q11203