SELL
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Official Full Name
selectin, lymphocyte -
Overview
L-Selectin encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, plus two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, which facilitates their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene -
Synonyms
CD62 antigen like family member L;CD62L;CD62L antigen;gp90 MEL;hLHRc;LAM 1;LAM1;LECAM1;Leu 8;LEU8;Leukocyte adhesion molecule 1;Leukocyte endothelial cell adhesion molecule 1;Leukocyte surface antigen Leu 8;LNHR;LSEL;Lyam 1;LYAM1;Lymph node homing receptor;lymphocyte adhesion molecule 1;pln homing receptor;PLNHR;selectin L;SELL;TQ1;L-selectin
Recombinant Proteins
- Mouse
- Human
- Cynomolgus
- Rhesus macaque
- Rat
- Zebrafish
- Bovine
- Mus musculus
- HEK293
- E.coli
- Mammalian cells
- CHO
- Mammalian Cell
- Human Cell
- E.coli expression system
- Insect Cell
- His
- His&Fc
- Fc
- Non
- His&GST
- GST
- His&Fc&Avi
Involved Pathway
SELL involved in several pathways and played different roles in them. We selected most pathways SELL participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with SELL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | HLA-E,PDCD1,HLA-DQA2,CLDNJ,NLGN2B,MHC2A,ITGA6B,MHC2DCB,JAM2,OCLNA |
Protein Function
SELL has several biochemical functions, for example, carbohydrate binding,cell adhesion molecule binding,glycosphingolipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SELL itself. We selected most functions SELL had, and list some proteins which have the same functions with SELL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| heparin binding | CCL23,VEGFA,BMP4,PCOLCE,SERPINC1,ANG,APPA,ABI3BP,RPL29,PGF |
| protein binding | SMCP,APLF,SDCCAG8,TRPC7,GHITM,F8,BMP4,NFKBIZ,BAG4,FZR1 |
| carbohydrate binding | CHIA,CLEC2G,CHODL,LGALS9L1,MRC2,KLRC1,Cd24a,Clec4n,GALNT13,CD302 |
| protease binding | MALT1,Serpina1b,PINK1,SERPINF2,TRP53,INS1,TIMP2A,POLG,KIT,SERPINB3 |
| glycosphingolipid binding | LAMC1,LAMB1,LAMA1,LYN,Cel,Il2,SELP |
| cell adhesion molecule binding | CD226,ITGB3,GLYCAM1,NLGN4X,CADM1A,NPTN,PVRL3B,VCAM1,PVRL1,CD1D |
Interacting Protein
SELL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SELL here. Most of them are supplied by our site. Hope this information will be useful for your research of SELL.
Resources
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References
- Cuong, NV; Carrique-Mas, J; et al. Rodents and Risk in the Mekong Delta of Vietnam: Seroprevalence of Selected Zoonotic Viruses in Rodents and Humans. VECTOR-BORNE AND ZOONOTIC DISEASES 15:65-72(2015).
- Gahoual, R; Biacchi, M; et al. Monoclonal antibodies biosimilarity assessment using transient isotachophoresis capillary zone electrophoresis-tandem mass spectrometry. MABS 6:1464-1473(2014).
