Recombinant Human SELL Protein, His-tagged

• Cat.No.: SELL-227H
• Product Overview: Recombinant Human SELL(52-345aa) fused with His tag at C-terminal was expressed in Insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 52-345aa
• Description: SELL, also known as L-selectin, is a cell surface component that is a member of a family of adhesion/homing receptors that play important roles in lymphocyte-endothelial cell interactions. This protein mediated lymphocyte recirculation is required for maintaining the appropriate tissue distribution of lymphocyte subpopulations including naive and effector subsets such as regulatory T cells. Importantly, this protein has been shown to have both adhesive and signaling functions during leukocyte migration.
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 34.1kDa (303aa) 40-57kDa (SDS-PAGE under reducing conditions)
• AA Sequence: ADPWTYHYSE KPMNWQRARR FCRDNYTDLV AIQNKAEIEY LEKTLPFSRS YYWIGIRKIG GIWTWVGTNK SLTEEAENWG DGEPNNKKNK
  EDCVEIYIKR NKDAGKWNDD ACHKLKAALC YTASCQPWSC SGHGECVEII NNYTCNCDVG YYGPQCQFVI QCEPLEAPEL GTMDCTHPLG
  NFSFSSQCAF SCSEGTNLTG IEETTCGPFG NWSSPEPTCQ VIQCEPLSAP DLGIMNCSHP LASFSFTSAC TFICSEGTEL IGKKKTICES
  SGIWSNPSPI CQKLDKSFSM IKEGDYNHHH HHH
• Purity: > 90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: SELL selectin L [ Homo sapiens ]
• Official Symbol: SELL
• Synonyms: SELL; selectin L; LNHR, LYAM1, lymphocyte adhesion molecule 1; L-selectin; CD62L; hLHRc; LAM 1; LAM1; Leu 8; LSEL; Lyam 1; PLNHR; gp90-MEL; pln homing receptor; lymph node homing receptor; lymphocyte adhesion molecule 1; leukocyte surface antigen Leu-8; CD62 antigen-like family member L; leukocyte-endothelial cell adhesion molecule 1; TQ1; LEU8; LNHR; LYAM1; LECAM1
• Gene ID: 6402
• mRNA Refseq: NM_000655
• Protein Refseq: NP_000646
• MIM: 153240
• UniProt ID: P14151