Recombinant Rat Adipoq, FLAG-tagged

• Cat.No.: Adipoq-195R
• Product Overview: Recombinant rat adiponectin encoding the mature peptide of rat adiponectin (amino acid His16~Asn244) was tagged with FLAG at the N-terminus. The tagged protein was expressed in a human embryonic kidney cell line,HEK293,and purified from conditioned media.

Specification

• Species: Rat
• Source: HEK293
• Tag: Flag
• Protein Length: 16-244 a.a.
• Description: Adiponectin, also known as apM1, Acrp30, GBP28 and adipoQ, is a circulating hormone predominantly produced from adipose tissue. Many pharmacological studies demonstrated that this protein possesses potent anti-diabetic, anti-atherogenic and anti-inflammatory functions. Supplement of adiponectin protein can decrease blood glucose, improve insulin sensitivity, alleviate fatty liver and prevent atherosclerosis. The protein is post-translationally modified by hydroxylation and glycosylation, and forms three different oligomeric complexes in the circulation.
• Formulation: 0.2 m filtered solution in phosphate-buffered saline.
• Activity: effect on the phosphorylation of acetyl-CoA carboxylase in C2C12 cells.
• Purity: >95%, as determined by SDS-PAGE.
• Endotoxin Level: <0.1EU/g, as determined by the LAL method.
• Stability Storage And Handling: The protein solution should be stored in working aliquots at -20°C for three months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: Adipoq adiponectin, C1Q and collagen domain containing [ Rattus norvegicus ]
• Synonyms: adiponectin, C1Q and collagen domain containing; Acdc; Acrp30; Adipoq; adiponectin; adipocyte complement related protein of 30 kDa
• Gene ID: 246253
• mRNA Refseq: NM_144744
• Protein Refseq: NP_653345
• Chromosome Location: 11q23
• Pathway: Adipocytokine signaling pathway; PPAR signaling pathway; Type II diabetes mellitus
• Function: eukaryotic cell surface binding; hormone activity; molecular_function; protein homodimerization activity