Recombinant Mouse Tpo Protein, Myc/DDK-tagged

• Cat.No.: Tpo-6603M
• Product Overview: Purified recombinant protein of mouse full-length thyroid peroxidase (Tpo), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a membrane-bound glycoprotein. The encoded enzyme plays a central role in thyroid gland function. The enzyme functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mice with homozygous missense mutations in this gene exhibit hypothyroid dwarfism and hearing impairment.
• Molecular Mass: 101.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tpo thyroid peroxidase [ Mus musculus (house mouse) ]
• Official Symbol: Tpo
• Synonyms: TPO; thyroid peroxidase
• Gene ID: 22018
• mRNA Refseq: NM_009417
• Protein Refseq: NP_033443
• UniProt ID: P35419