Native Human Thyroid Peroxidase

• Cat.No.: TPO-8266H
• Product Overview: Human Thyroid Peroxidase was purified from Human Thyroid Tissue.

Specification

• Species: Human
• Source: Human Thyroids
• Tag: Non
• Description: Human Thyroid peroxidase (TPO) is an enzyme mainly expressed in the thyroid that liberates iodine for addition onto tyrosine residues on thyroglobulin for the production of thyroxine (thyroid hormone).
• Form: Frozen Liquid with sodium azide as a preservative
• Purity: >90% pure by SDS PAGE
• Stability: 1 year
• Storage: -20 °C
• Concentration: Typically >1.0 mg/mL

Gene Information

• Gene Name: TPO thyroid peroxidase [ Homo sapiens ]
• Official Symbol: TPO
• Synonyms: TPO; thyroid peroxidase; TPX; thyroperoxidase; thyroid microsomal antigen; MSA; TDH2A
• Gene ID: 7173
• mRNA Refseq: NM_000547
• Protein Refseq: NP_000538
• MIM: 606765
• UniProt ID: P07202
• Chromosome Location: 2p25
• Pathway: Amine-derived hormones, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem
• Function: calcium ion binding; heme binding; iodide peroxidase activity; oxidoreductase activity; peroxidase activity