Recombinant Mouse Rarg Protein, Myc/DDK-tagged

• Cat.No.: Rarg-5381M
• Product Overview: Purified recombinant protein of mouse full-length retinoic acid receptor, gamma (Rarg), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 50.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rarg retinoic acid receptor, gamma [ Mus musculus (house mouse) ]
• Official Symbol: Rarg
• Synonyms: RARG; retinoic acid receptor, gamma; retinoic acid receptor gamma; RAR-gamma; RAR gamma 2; nuclear receptor subfamily 1 group B member 3; RARD; Nr1b3; AI385767; RARgamma2; MGC11555; MGC18523
• Gene ID: 19411
• mRNA Refseq: NM_011244
• Protein Refseq: NP_035374
• UniProt ID: P18911