Recombinant Human RARG, GST-tagged

• Cat.No.: RARG-31059TH
• Product Overview: Recombinant full length Human Retinoic Acid Receptor gamma with C-Terminal GST tag expressed in a baculovirus system, Predicted MWt 76 kDa.

Specification

• Description: This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Conjugation: GST
• Biological activity: 1 unit equals 1 nanogram of purified protein.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Full Length: Full L.

Gene Information

• Gene Name: RARG retinoic acid receptor, gamma [ Homo sapiens ]
• Official Symbol: RARG
• Synonyms: RARG; retinoic acid receptor, gamma; retinoic acid receptor gamma; NR1B3; RARC
• Gene ID: 5916
• mRNA Refseq: NM_000966
• Protein Refseq: NP_000957
• MIM: 180190
• Uniprot ID: P13631
• Chromosome Location: 12q13
• Pathway: Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear receptors in lipid metabolism and toxicity, organism-specific biosystem
• Function: DNA binding; metal ion binding; protein binding; receptor activity; retinoic acid receptor activity