Recombinant Mouse Ptpn1 Protein, Myc/DDK-tagged

• Cat.No.: Ptpn1-5234M
• Product Overview: Purified recombinant protein of mouse full-length protein tyrosine phosphatase, non-receptor type 1 (Ptpn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 49.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ptpn1 protein tyrosine phosphatase, non-receptor type 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ptpn1
• Synonyms: PTPN1; protein tyrosine phosphatase, non-receptor type 1; tyrosine-protein phosphatase non-receptor type 1; protein-tyrosine phosphatase 1B; protein-tyrosine phosphatase HA2; protein-protein-tyrosine phosphatase HA2; PTP1B; PTP-1B; PTP-HA2
• Gene ID: 19246
• mRNA Refseq: NM_011201
• Protein Refseq: NP_035331
• UniProt ID: P35821