Recombinant Mouse Itgae Protein, Myc/DDK-tagged

• Cat.No.: Itgae-3600M
• Product Overview: Purified recombinant protein of mouse full-length integrin alpha E, epithelial-associated (Itgae), transcript variant 2, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 115.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Itgae integrin alpha E, epithelial-associated [ Mus musculus (house mouse) ]
• Official Symbol: Itgae
• Synonyms: ITGAE; integrin alpha E, epithelial-associated; integrin alpha-E; integrin alpha M290; CD103; aM290; alpha-E1; A530055J10; alpha-M290; MGC183601
• Gene ID: 16407
• mRNA Refseq: NM_172944
• UniProt ID: Q60677