Recombinant Mouse Ctsl Protein, His-tagged
Cat.No. : | Ctsl-38M |
Product Overview : | Recombinant mouse CTSL, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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Description : | CTSL, also known as cathepsin L1, is a lysosomal cysteine protease expressed in most eukaryotic cells. It plays a major role in intracellular protein catabolism and is potent in degrading collagen, laminin, elastin, as well as alpha-1 protease inhibitor and other structural proteins of basement membranes. |
Source : | Insect cells |
Species : | Mouse |
Tag : | His tag |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 36.8kDa (325aa)40-57KDa (SDS-PAGE under reducing conditions.) |
AA Sequence : | TPKFDQTFSA EWHQWKSTHR RLYGTNEEEW RRAIWEKNMR MIQLHNGEYS NGQHGFSMEM NAFGDMTNEE FRQVVNGYRH QKHKKGRLFQEPLMLKIPKS VDWREKGCVT PVKNQGQCGS CWAFSASGCL EGQMFLKTGK LISLSEQNLV DCSHAQGNQG CNGGLMDFAF QYIKENGGLDSEESYPYEAK DGSCKYRAEF AVANDTGFVD IPQQEKALMK AVATVGPISV AMDASHPSLQ FYSSGIYYEP NCSSKNLDHG VLLVGYGYEGTDSNKNKYWL VKNSWGSEWG MEGYIKIAKD RDNHCGLATA ASYPVVNLEH HHHHH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25mg/ml (determined by Absorbance at 280nm) |
Gene Name | Ctsl cathepsin L [ Mus musculus ] |
Official Symbol | Ctsl |
Synonyms | Cathepsin L1; CTSL; CatL; Ctsl1; fs; MEP; nkt |
Gene ID | 13039 |
mRNA Refseq | NM_009984 |
Protein Refseq | NP_034114 |
MIM | |
UniProt ID | P06797 |
Chromosome Location | 13 B3; 13 33.26 cM |
Pathway | Antigen processing and presentation, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; PodNet: protein-protein interactions in the podocyte, organism-specific biosystem |
Function | aminopeptidase activity; cysteine-type carboxypeptidase activity; histone binding |
Not For Human Consumption!
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