Recombinant Mouse Angpt4 protein, His & GST-tagged

• Cat.No.: Angpt4-751M
• Product Overview: Recombinant Mouse Angpt4 aa. (Phe32~Pro144) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene is a member of the angiopoietin family of secreted growth factors comprising Angiopoietins-1, -2, and -3, all of which bind the TEK Receptor Tyrosine Kinase. Angiopoietin/TEK Receptor Tyrosine Kinase signaling is involved in survival and migration of endothelial cells and regulates vascular remodeling and maintenance of vascular integrity. Angiopoietin/TEK Receptor Tyrosine Kinase signaling is also required for lymphangiogenesis. Family members bind TEK Receptor Tyrosine Kinase as multimeric clusters but their oligomerization properties differ from one another and this is thought to provide a mechanistic basis for their distinct physiologic roles.
• Source: E. coli
• Species: Mouse
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 40.0kDa
• Protein length: Phe32~Pro144
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.2.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Angpt4 angiopoietin 4 [ Mus musculus (house mouse) ]
• Official Symbol: Angpt4
• Synonyms: Ang3; ANG-3; ANG-4; Agpt4; angiopoietin-4; angiopoietin-3
• Gene ID: 11602
• mRNA Refseq: NM_009641.2
• Protein Refseq: NP_033771.1
• UniProt ID: Q9WVH6