Recombinant Mouse Angiopoietin 4

• Cat.No.: Angpt4-2519M

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Non
• Description: Angiopoietin-4 is a protein that in humans is encoded by the ANGPT4 gene. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin.
• Analysis Note: The biological activity is measured by its ability to bind immobilized Tie-2/Fc in ELISA.
• Form: lyophilized powder.
• Mol Wt: apparent mol wt 85-90 kDa by SDS-PAGE (reducing) calculated mol wt ~58 kDa.
• Total Impurities: endotoxin, tested.
• Physical Form: Lyophilized from a 0.2 μm filtered solution in 50 mM Tris citrate and 0.5 M sodium chloride, pH 6.5, containing 1.25 mg bovine serum albumin.
• Assay: ≥90% (SDS-PAGE).
• Storage Temp: −20°C.

Gene Information

• Gene Name: Angpt4 angiopoietin 4 [ Mus musculus ]
• Synonyms: angiopoietin 4; Ang3; Agpt4; MGC156453; Angpt4; angiopoietin-4; ANG-3; ANG-4 angiopoietin 3; angiopoietin-3; OTTMUSP00000016888
• Gene ID: 11602
• mRNA Refseq: NM_009641
• Protein Refseq: NP_033771
• UniProt ID: Q9WVH6
• Chromosome Location: 2 G3; 2 84.0 cM
• Function: receptor binding; vascular endothelial growth factor receptor binding