Recombinant Mouse Acvr1c Protein, Myc/DDK-tagged

• Cat.No.: Acvr1c-1523M
• Product Overview: Purified recombinant protein of mouse full-length activin A receptor, type IC (Acvr1c), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Protein Length: 1-493aa
• Description: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
• Molecular Mass: 41.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Acvr1c activin A receptor, type IC [ Mus musculus (house mouse) ]
• Official Symbol: Acvr1c
• Synonyms: ACVR1C; activin A receptor, type IC; activin receptor type-1C; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7; ALK7; Alk-7; ACVRLK7; C230097P10
• Gene ID: 269275
• mRNA Refseq: NM_001033369
• Protein Refseq: NP_001028541
• UniProt ID: Q3V348