Recombinant Human ACVR1C Protein, His tagged
Cat.No. : | ACVR1C-839H |
Product Overview : | Recombinant Human ACVR1C Protein with C-His tag was expressed in Baculovirus-Insect Cells. |
Availability | March 16, 2025 |
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Species : | Human |
Source : | Insect Cells |
Tag : | His |
Protein Length : | 135-493 aa |
Description : | ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors. |
Tag : | C-His |
Molecular Mass : | 43 kDa |
AA Sequence : | MACQGRQCSYRKKKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERYWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTMAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKALVPRGSHHHHHHHH |
Purity : | > 80% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Sterile 50mM Tris, pH7.5, 150mM NaCl, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% Glycerol, 500mM Arginine. |
Concentration : | 0.75 mg/mL by Bradford |
Gene Name | ACVR1C activin A receptor type 1C [ Homo sapiens (human) ] |
Official Symbol | ACVR1C |
Synonyms | ACVR1C; activin A receptor, type IC; activin receptor type-1C; ACVRLK7; ALK7; ALK-7; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7; |
Gene ID | 130399 |
mRNA Refseq | NM_001111031 |
Protein Refseq | NP_001104501 |
MIM | 608981 |
UniProt ID | Q8NER5 |
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◆ Cell & Tissue Lysates | ||
ACVR1C-1277CCL | Recombinant Cynomolgus ACVR1C cell lysate | +Inquiry |
Not For Human Consumption!
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