Recombinant Human Transforming Growth Factor, Alpha
| Cat.No. : | TGFA-5521H |
| Product Overview : | Recombinant Human TGFAcomprises the human TGF-alpha amino acid sequence plus a 14 amino acidN-terminal extension peptide. |
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| Cat. No. : | TGFA-5521H |
| Description : | This product is alow cost, potent analog of human TGF-alpha. The recombinant growth factor canbe used as a supplement for serum-free or low serum cell culture. It is alsosuitable for cultured fibroblasts, particularly from avian species used inthe production of viral vaccines. |
| Source : | E. coli |
| Species : | Human |
| Form : | Lyophilized whitepowder. Dried from 0.1 M acetic acid and stored under nitrogen at a slightvacuum. |
| Purity : | > 90% (byN-terminal sequence analysis). |
| Molecular Weight : | 7113Daltons-confirmed by Mass Spectrometry (minor N-terminal formylated form of7142 Daltons). |
| N-terminal SequenceAnalysis : | 18 residues > 96% single sequence. |
| Biological Activity : | Cell proliferationin Balb/c 3T3 fibroblasts: ED50 <20 ng/ml (in the presence of100 ng/ml Long TMR3IGF-I). |
| Endotoxin : | < 0.1 EU/μg |
| Reconstitution : | Handling of GroPepLONG™EGF and LONG™TGF-α. |
| Storage : | At least 2 years at2 - 4°C (lyophilized). |
| OfficialSymbol : | TGFA |
| Pathways : | Direct p53effectors; ErbB receptor signaling network; ErbB signaling pathway; FOXM1transcription factor network; Glioma; Non-small cell lung cancer; Pancreaticcancer; Pathways in cancer; Prostate cancer; Renal cell carcinoma |
| Tag : | Non |
| Gene Name | TGFA transforming growth factor,alpha [ Homo sapiens ] |
| Synonyms | TGFA; transforminggrowth factor, alpha; TFGA; protransforming growth factor alpha;TGF-alpha; OTTHUMP00000160075; OTTHUMP00000203300; OTTHUMP00000203301;OTTHUMP00000203345; OTTHUMP00000203352; OTTHUMP00000225517; Protransforming growth factor alpha;Transforming growth factor alpha |
| Gene ID | 7039 |
| mRNA Refseq | NM_001099691 |
| Protein Refseq | NP_001093161 |
| MIM | 190170 |
| UniProt ID | P01135 |
| Chromosome Location | 2p13 |
| Function | MAP kinase kinaseactivity; epidermal growth factor receptor binding; glycoprotein binding;growth factor activity; protein binding; signal transducer activity |
Not For Human Consumption!
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