Recombinant Human thyroid stimulating hormone receptor Protein, His tagged

• Cat.No.: TSHR-14H
• Product Overview: Recombinant human Thyroid Stimulating Hormone Receptor produced in E. coli forms a dimer migrating at 46 kDa on SDS-PAGE. TSHR human contains multiple Leucine rich repeats with a histidine tag at N-terminus and purified by proprietary chromatographic technique.

Specification

• Description: The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: N-His
• Protein length: Full Length
• Form: Sterile Filtered clear solution.
• Molecular Mass: 46 kDa
• Purity: > 85%
• Applications: TSH receptor autoantibody.
• Notes: Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
• Storage: Store at 4 centigrade if entire vial will be used within 2-4 weeks. Store, frozen at -20 centigrade for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
• Storage Buffer: PBS & 25mM K2CO3.
• Shipping: Ice Packs

Gene Information

• Gene Name: TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ]
• Official Symbol: TSHR
• Synonyms: TSHR; thyroid stimulating hormone receptor; thyrotropin receptor; TSH receptor; seven transmembrane helix receptor; thyrotropin receptor-I, hTSHR-I
• Gene ID: 7253
• mRNA Refseq: NM_000369
• Protein Refseq: NP_000360
• MIM: 603372
• UniProt ID: Q59GA2