Recombinant Human TAR DNA Binding Protein, T7-tagged

• Cat.No.: TARDBP-2993H
• Product Overview: Recombinant Human TARDBP protein, fused with a T7-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques, 44740Da (414aa).

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Description: TAR DNA-binding protein 43 (TDP-43), is a cellular protein which in humans is encoded by the TARDBP gene.
• Sequences of amino acids: MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKIPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA EPKHNSNRQL ERSGRFGGNP GGFGNQGGFG NSRGGGAGLG NNQGSNMGGG MNFGAFSINP AMMAAAQAAL QSSWGMMGML ASQQNQSGPS GNNQNQGNMQ REPNQAFGSG NNSYSGSNSG AAIGWGSASN AGSGSGFNGG FGSSMDSKSS GWGM
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3
• Purity: 95% by SDS - PAGE
• Applications: MS. SDS

Gene Information

• Gene Name: TARDBP TAR DNA binding protein [Homo sapiens]
• Synonyms: TARDBP; TDP-43; TAR DNA binding protein; ASL 10; TAR DNA-binding protein 43; TDP43; TAR DNA-binding protein 43; OTTHUMP00000002173; TRA DNA-binding protein-43
• Gene ID: 23435
• mRNA Refseq: NM_007375
• Protein Refseq: NP_003140
• MIM: 605078
• UniProt ID: Q13148
• Chromosome Location: 1p36.22
• Function: DNA binding; RNA binding; double-stranded DNA binding; mRNA 3'-UTR binding; nucleotide binding; protein binding; sequence-specific DNA binding transcription factor activity