Recombinant Human SOX6 Protein, His-tagged

• Cat.No.: SOX6-2721H
• Product Overview: Recombinant Human SOX6 Protein (Met1-Pro269) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: Met1-Pro269
• Description: This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 34.4 kDa
  Accurate Molecular Mass: 38 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: SOX6 SRY (sex determining region Y)-box 6 [ Homo sapiens (human) ]
• Official Symbol: SOX6
• Synonyms: SOX6; SRY (sex determining region Y)-box 6; transcription factor SOX-6; SRY-box containing gene 6; SOXD; HSSOX6
• Gene ID: 55553
• mRNA Refseq: NM_001145811
• Protein Refseq: NP_001139283
• MIM: 607257
• UniProt ID: P35712