Recombinant Human SMARCA2 Protein, His-tagged, Biotinylated

• Cat.No.: SMARCA2-194HB
• Product Overview: Recombinant Human SMARCA2 protein, fused with N-terminal His-tag, was expressed in E. coli. The purified recombinant protein was labeled with Biotin.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1367-1511 aa
• Description: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
• Form: 25 mM HEPES pH 7.5, 150 mM NaCl, 5% glycerol (v/v).
• Molecular Mass: 19.6 kDa
• Purity: ≥90% (SDS-PAGE)
• Storage: Store at -80 centigrade. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles.
• Concentration: 0.65 mg/ml

Gene Information

• Gene Name: SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 [ Homo sapiens (human) ]
• Official Symbol: SMARCA2
• Synonyms: BIS; BRM; SNF2; SWI2; hBRM; NCBRS; Sth1p; BAF190; SNF2L2; SNF2LA; hSNF2a
• Gene ID: 6595
• mRNA Refseq: NM_139045.4
• Protein Refseq: NP_620614.2
• MIM: 600014
• UniProt ID: P51531