Recombinant Human SMAD6, His-tagged

• Cat.No.: SMAD6-2801H
• Product Overview: Recombinant Human SMAD6 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-496aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: SMAD6 SMAD family member 6 [ Homo sapiens ]
• Official Symbol: SMAD6
• Synonyms: SMAD6; SMAD family member 6; MAD, mothers against decapentaplegic homolog 6 (Drosophila) , MADH6, MADH7, SMAD, mothers against DPP homolog 6 (Drosophila); mothers against decapentaplegic homolog 6; HsT17432; SMAD 6; hSMAD6; MAD homolog 6; mothers against DPP homolog 6; SMAD, mothers against DPP homolog 6; Mothers against decapentaplegic, drosophila, homolog of, 6; MADH6; MADH7
• Gene ID: 4091
• mRNA Refseq: NM_001142861
• Protein Refseq: NP_001136333
• MIM: 602931
• UniProt ID: O43541
• Chromosome Location: 15q21-q22
• Pathway: BMP receptor signaling, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; Signaling by TGF beta, organi
• Function: I-SMAD binding; R-SMAD binding; chromatin binding; co-SMAD binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transforming growth factor beta receptor, inhibitory cytoplasmic