Recombinant Human Secreted Phosphoprotein 1, GST-tagged

• Cat.No.: SPP1-815H
• Product Overview: Recombinant SPP1 protein was expressed in E.coli and purified by affinity chromatography, 55866,6 Da

Specification

• Cat. No.: SPP1-815H
• Description: Osteopontin (OPN), also known as bone sialoprotein I (BSP-1 or BNSP), early T-lymphocyte activation (ETA-1), secreted phosphoprotein 1 (SPP1), 2ar and Rickettsia resistance (Ric), is a human gene product,which is also conserved in other species. Osteopontin is a SIBLING glycoprotein that was first identified in 1986 in osteoblasts. The prefix of the word "osteo" indicates that the protein is expressed in bone, although it is also expressed in other tissues. The suffix "-pontin" is derived from "pons," the Latin word for bridge, and signifies osteopontin"s role as a linking protein. Osteopontin is an extracellular structural protein and therefore an organic component of bone.
• Sequences of amino acids: 59-300 aa
• Formulation: Lyophilized from a solution of phosphate buffered saline (PBS), pH 7.4, purified by affinity chromatography.

Gene Information

• Gene Name: SPP1 secreted phosphoprotein 1 [ Homo sapiens ]
• Synonyms: OPN; BNSP; BSPI; ETA-1; MGC110940; SPP1; osteopontin; SPP-1; uropontin; nephropontin; OTTHUMP00000218556; SPP1/CALPHA1 fusion; bone sialoprotein 1; bone sialoprotein I; urinary stone protein; early T-lymphocyte activation 1; secreted phosphoprotein-1; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein;secreted phosphoprotein 1; SPP1/CALPHA1 fusion
• Gene ID: 6696
• mRNA Refseq: NM_000582
• Protein Refseq: NP_000573
• MIM: 166490
• UniProt ID: P10451
• Chromosome Location: 4q22.1
• Pathway: ECM-receptor interaction; Focal adhesion; Toll-like receptor signaling pathway; Integrin cell surface interactions; Signaling by PDGF
• Function: cytokine activity