Recombinant Human RET protein, Flag-tagged, Biotinylated

• Cat.No.: RET-75H
• Product Overview: Recombinant Human RET, cytoplasmic domain [658-1114(end) amino acids of accession number NP_066124.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Flag
• Protein Length: 658-1114 a.a.
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 56 kDa
• Purity: >90% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: RET ret proto-oncogene [ Homo sapiens ]
• Official Symbol: RET
• Synonyms: RET; ret proto-oncogene; CDHF12; CDHR16; PTC; RET51; MTC1; HSCR1; MEN2A; MEN2B; RET-ELE1
• Gene ID: 5979
• mRNA Refseq: NM_020630
• Protein Refseq: NP_065681
• UniProt ID: P07949
• Chromosome Location: 10q11.2
• Pathway: Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Pathways in cancer, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem; Signaling events regulated by Ret tyrosine kinase, organism-specific biosystem; Thyroid cancer, organism-specific biosystem; Thyroid cancer, conserved biosystem
• Function: ATP binding; calcium ion binding; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity