Recombinant Human Renin
Cat.No. : | REN-5473H |
Product Overview : | Recombinantlyproduced in HEK cell culture as untagged native form prorenin and purified byaffinity chromatography. |
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Species : | Human |
Source : | HEK293 |
Tag : | Non |
Description : | REN is aglycosylated aspartic protease that consists of 2 homologous lobes and is theprecursor of renin. Prorenin exhibits a low level of enzymatic activityrelative to renin which is generated from prorenin by proteolytic cleavage ofthe first 43 amino acids at the N-terminus. This so-called prosegment appearsto block the full enzymatic potential of the active site. |
Form : | Frozen liquid in 10mM Tris Buffer + 0.1 M NaCl, pH 8.0. |
Purity : | >95% by SDS-PAGEanalysis |
MolecularWeight : | 43.725 kDa |
Endotoxin Level : | < 0.1 ng/μg ofprotein |
Concentration : | 1.0 mg/ml |
Storage : | Store at -80°C.Stable for 3 years from delivery. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | REN |
Pathways : | ACE InhibitorPathway; Renin-angiotensin system |
Gene Name | REN renin [ Homo sapiens] |
Synonyms | REN;renin; HNFJ2; OTTHUMP00000034311; angiotensinogenase; reninprecursor, renal; angiotensin-forming enzyme; EC 3.4.23.15; Renin; Angiotensinogenase |
Gene ID | 5972 |
mRNA Refseq | NM_000537 |
Protein Refseq | NP_000528 |
MIM | 179820 |
UniProt ID | P00797 |
Chromosome Location | 1q32 |
Function | aspartic-typeendopeptidase activity; insulin-like growth factor receptor binding;peptidase activity; receptor binding |
◆ Recombinant Proteins | ||
REN-1111H | Active Recombinant Human REN Protein, His-tagged | +Inquiry |
REN-5164H | Recombinant Human REN Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
REN-700D | Recombinant Dog Renin, His-tagged | +Inquiry |
Ren-695R | Recombinant Rat Ren protein, His-tagged | +Inquiry |
REN-317H | Recombinant Full Length Human REN, His tagged | +Inquiry |
◆ Native Proteins | ||
REN-388H | Active Native Human Renin Antigen | +Inquiry |
Ren -72R | Recombinant Rat Prorenin, His tag | +Inquiry |
REN-245H | Active Native Human Renin | +Inquiry |
REN -16H | Recombinant Human Prorenin, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
REN-2862HCL | Recombinant Human REN cell lysate | +Inquiry |
Not For Human Consumption!
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