Active Native Human Renin

• Cat.No.: REN-245H
• Product Overview: Purified Native Human Kidney Renin. E.C. Number: 3.4.23.15

Specification

• Species: Human
• Source: Human Kidney
• Tag: Non
• Description: Early detection of HUMAN RENIN level increases related to blood pressure increase have shown in research to provide vital prognostic and diagnostic guidelines for evaluating possible surgical treatment especially in renovascular involvement.
• Form: Liquid
• Bio-activity: Typically >1 u/mL
• Purity: >90%
• Unit Definition: Renin Activity was measured by following the cleavage of the fluorogenic substrate Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg at pH 8.0 and 37C
• Storage: Store at 2-8 °C.
• Concentration: Typically >0.1 mg protein/mL

Gene Information

• Gene Name: REN renin [ Homo sapiens ]
• Official Symbol: REN
• Synonyms: REN; renin; angiotensinogenase; renin precursor, renal; angiotensin-forming enzyme; HNFJ2; FLJ10761
• Gene ID: 5972
• mRNA Refseq: NM_000537
• Protein Refseq: NP_000528
• MIM: 179820
• UniProt ID: P00797
• Chromosome Location: 1q32
• Pathway: ACE Inhibitor Pathway, organism-specific biosystem; Renin-angiotensin system, organism-specific biosystem; Renin-angiotensin system, conserved biosystem
• Function: aspartic-type endopeptidase activity; insulin-like growth factor receptor binding; peptidase activity; receptor binding