Recombinant Human RAPGEF3, GST-tagged

• Cat.No.: RAPGEF3-1022H
• Product Overview: Recombinant Human RAPGEF3 (1 aa. - 881 aa.) fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: Rap guanine nucleotide exchange factor 3 is a protein that in humans is encoded by the RAPGEF3 gene.
• Molecular Mass: 125.8 kDa
• Sequence: MVLRRMHRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEPVGTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
• Storagebuffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
• Applications: ELISA; WB
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• OfficialSymbol: RAPGEF3

Gene Information

• Gene Name: RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 [ Homo sapiens ]
• Synonyms: RAPGEF3; Rap guanine nucleotide exchange factor (GEF) 3; EPAC; EPAC1; bcm910; HSU79275; MGC21410; CAMP-GEFI; Rap guanine nucleotide exchange factor 3; 9330170P05Rik; exchange protein directly activated by cAMP 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; cAMP-GEFI; cAMP-regulated guanine nucleotide exchange factor I; Epac 1
• Gene ID: 10411
• mRNA Refseq: NM_006105
• Protein Refseq: NP_006096
• MIM: 606057
• UniProt ID: O95398
• Chromosome Location: 12q13.1
• Pathway: Leukocyte transendothelial migration; Long-term potentiation; Diabetes pathways; Hemostasis; Integrin cell surface interactions
• Function: cAMP binding; cAMP-dependent protein kinase regulator activity; guanyl-nucleotide exchange factor activity; protein binding