Recombinant Human PFN2 Protein

• Cat.No.: PFN2-644H
• Product Overview: Recombinant Human PFN2, transcript variant 1, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM Tris, 150mM NaCl, pH 8.0
• Molecular Mass: 15kD
• AA Sequence: MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLALGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: PFN2 profilin 2 [ Homo sapiens ]
• Official Symbol: PFN2
• Synonyms: PFN2; profilin 2; profilin-2; profilin II; PFL; D3S1319E
• Gene ID: 5217
• mRNA Refseq: NM_002628
• Protein Refseq: NP_002619
• MIM: 176590
• UniProt ID: P35080