Recombinant Human PAX8 Protein, His-tagged

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Description :	This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
Source :	E. coli
Species :	Human
Tag :	His
Form :	Freeze-dried powder
Molecular Mass :	Predicted Molecular Mass: 19.4 kDa Accurate Molecular Mass: 19 kDa
Protein length :	Met1-Pro143
Endotoxin :	<1.0 EU per 1µg (determined by the LAL method).
Purity :	> 90%
Applications :	Positive Control; Immunogen; SDS-PAGE; WB.
Stability :	The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage :	Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer :	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Reconstitution :	Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Name	PAX8 paired box 8 [ Homo sapiens (human) ]
Official Symbol	PAX8
Synonyms	PAX8; paired box 8; paired box gene 8; paired box protein Pax-8; paired domain gene 8;
Gene ID	7849
mRNA Refseq	NM_003466
Protein Refseq	NP_003457
MIM	167415
UniProt ID	Q06710